Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.56 |
| ▸ | MMP3 | P08254 | 3/20 | 0.56 |
| ▸ | MMP7 | P09237 | 2/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.48 |
| ▸ | LGMN | Q99538 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4133018 | 0.91 | MMP1 (0.56) | MMP1MMP3MMP7MMP13NPC1 | |
| SCHEMBL5087589 | 0.88 | RAB9A (0.55) | MMP1MMP3MMP7MMP13NPC1 | |
| SCHEMBL3764050 | 0.83 | BDKRB1 (0.41) | MMP1MMP3MMP7MMP13NPC1 | |
| SCHEMBL3764045 | 0.83 | BDKRB1 (0.41) | MMP1MMP3MMP7MMP13NPC1 | |
| SCHEMBL3802057 | 0.82 | LOX (0.50) | RAB9AFKBP1A | |
| SCHEMBL8207295 | 0.82 | MMP1 (0.61) | MMP1MMP3MMP7MMP13NPC1 | |
| SCHEMBL2568316 | 0.82 | MEN1 (0.52) | MMP1MMP3MMP7MMP13NPC1 | |
| SCHEMBL6977510 | 0.81 | MMP1 (0.63) | MMP1MMP3MMP7MMP13NPC1 | |
| SCHEMBL2566355 | 0.81 | NPC1 (0.49) | MMP1MMP3MMP7MMP13NPC1 | |
| SCHEMBL13037004 | 0.81 | PSEN1 (0.71) | MMP1MMP3MMP7MMP13NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | MMP1 4574/4885MMP3 4072/4885MMP7 2964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.