Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 2/20 | 0.59 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.59 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.59 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.59 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.59 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GCGR | P47871 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533800 | 1.00 | GRIN2D (0.59) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL31511413 | 1.00 | GRIN2D (0.59) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7898857 | 1.00 | GRIN2D (0.59) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3336161 | 0.83 | TSHR (0.53) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL11342221 | 0.82 | GRIN2D (0.69) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3080925 | 0.82 | GRIN2D (0.69) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL30427622 | 0.82 | GRIN2D (0.69) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL27516598 | 0.82 | ALDH1A1 (0.48) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL4272121 | 0.81 | HPGD (0.55) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL4272126 | 0.81 | HPGD (0.55) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113979871-B | Preparation method of N-methyl-1-naphthylmethylamine and intermediate N-methyl-1-naphthylmethylamine | 江苏同禾药业有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-113979871-A | Preparation method of N-methyl-1-naphthylmethylamine and intermediate N-methyl-1-naphthylmethylamine | 江苏同禾药业有限公司 | 2022-01-28 | — | — | CN | claimed |
| EP-1527165-A4 | A RHODOCOCCUS GENE ENCODING ALDOXIME DEHYDRATASE | DU PONT (US) | 2006-06-07 | — | — | EP | claimed |
| EP-1527165-A2 | A RHODOCOCCUS GENE ENCODING ALDOXIME DEHYDRATASE | E.I. du Pont de Nemours and Company (US) | 2005-05-04 | — | — | EP | claimed |
| US-20030215929-A1 | Rhodococcus gene encoding aldoxime dehydratase | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-11-20 | — | — | US | claimed |
| WO-2003078581-A2 | A RHODOCOCCUS GENE ENCODING ALDOXIME DEHYDRATASE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-09-25 | — | — | WO | claimed |
| US-6335450-B1 | FLUORSECENT LABELING | BECKMAN COULTER, INC. | 2002-01-01 | — | — | US | claimed |
| EP-0009103-B1 | N-(O-ETHYL-S-N-PROPYL-(DI)THIOPHOSPHORYLOXY)-NAPHTALIMIDES, PROCESS FOR THEIR PREPARATION, PESTICIDAL COMPOSITIONS CONTAINING THEM, THEIR PREPARATION AND USE | BAYER AG (DE) | 1981-04-29 | — | — | EP | claimed |
| US-12570675-B2 | Boronic acid compounds | LG CHEM, LTD. (KR) | 2026-03-10 | — | — | US | disclosed |
| US-20240167176-A1 | STIRRING-FREE SCALABLE ELECTROSYNTHESIS ENABLED BY ALTERNATING CURRENT | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2024-05-23 | — | — | US | disclosed |
| US-20240101579-A1 | BORONIC ACID COMPOUNDS | LG CHEM, LTD. (KR) | 2024-03-28 | — | — | US | disclosed |
| CN-116535399-B | 3-hydroxy-5- (isoxazol-5-yl) pyridine formyl glycine compound, preparation method, pharmaceutical composition and application | 中国药科大学 | 2024-02-27 | — | — | CN | disclosed |
| CN-113979871-B | Preparation method of N-methyl-1-naphthylmethylamine and intermediate N-methyl-1-naphthylmethylamine | 江苏同禾药业有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-113979871-B | Preparation method of N-methyl-1-naphthylmethylamine and intermediate N-methyl-1-naphthylmethylamine | 江苏同禾药业有限公司 | 2023-11-10 | — | — | CN | disclosed |
| EP-0313997-A2 | Medicine, therein contained phosphor containing 2-isoxazolidines and isoxazoles, as well as process for preparing those heterocyclic compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-03 | — | — | EP | disclosed |
| EP-0293058-A2 | A positive photosensitive resinous composition | Nippon Paint Co., Ltd. (JP) | 1988-11-30 | — | — | EP | disclosed |
| EP-0112524-B1 | TRICHLOROACRYLOYL OXIME DERIVATIVES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-05-28 | — | — | EP | disclosed |
| US-4581365-A | Trichloroacryloyl oxime fungicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-04-08 | — | — | US | disclosed |
| EP-0112524-A1 | Trichloroacryloyl oxime derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-07-04 | — | — | EP | disclosed |
| US-4248866-A | Combating arthropods with N-(O-ethyl-S-n-propyl-thiophosphoryloxy)-naphthalimides | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12570675-B2 | Boronic acid compounds | PSMB6, PSMB3, PSMB2 | GRIN2D 4036/4885GRIN3B 3940/4885GRIN1 2816/4885 |
| US-20240101579-A1 | BORONIC ACID COMPOUNDS | PSMB11, PSMB1, BACH1 | GRIN2D 4815/4885GRIN3B 4599/4885GRIN1 3107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.