Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4141606 | 0.95 | ENPP2 (0.41) | ENPP2TERTCYP2D6KDM4EALDH1A1 | |
| SCHEMBL4145137 | 0.89 | ENPP2 (0.46) | ENPP2TERTCYP2D6KDM4EALDH1A1 | |
| SCHEMBL4147314 | 0.87 | ENPP2 (0.49) | ENPP2TERTCYP2D6KDM4EALDH1A1 | |
| SCHEMBL3083109 | 0.87 | TERT (0.37) | ENPP2TERT | |
| SCHEMBL6515386 | 0.82 | ENPP2 (0.52) | ENPP2TERTCYP2D6KDM4EALDH1A1 | |
| SCHEMBL4141501 | 0.82 | ENPP2 (0.52) | ENPP2TERTCYP2D6KDM4EALDH1A1 | |
| SCHEMBL29965184 | 0.82 | ENPP2 (0.52) | ENPP2TERTCYP2D6KDM4EALDH1A1 | |
| SCHEMBL4134381 | 0.82 | ENPP2 (0.46) | ENPP2TERTCYP2D6KDM4EALDH1A1 | |
| SCHEMBL3081613 | 0.81 | TERT (0.36) | ENPP2TERT | |
| SCHEMBL3089988 | 0.77 | TERT (0.41) | ENPP2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541633-A | Ink jet printing of concealed images on carbonless paper | XEROX CORPORATION (US) | 1996-07-30 | — | — | US | claimed |
| US-5286286-A | Containing diethylene glycol monobutyl ether, glycerol, and a dansyl or porphyrin chromophores | XEROX CORPORATION (US) | 1994-02-15 | — | — | US | claimed |
| US-5256193-A | Porphyrin chromophore and dendrimer ink composition | XEROX CORPORATION (US) | 1993-10-26 | — | — | US | claimed |
| US-20090008452-A1 | PRODUCT PACKAGING INCLUDING DIGITAL DATA | VERIFICATION TECHNOLOGIES, INC. (US) | 2009-01-08 | — | — | US | disclosed |
| US-20080011853-A1 | Product Packaging Including Digital Data | VERIFICATION TECHNOLOGIES, INC. (US) | 2008-01-17 | — | — | US | disclosed |
| US-7237720-B2 | Product packaging including digital data | VERIFICATION TECHNOLOGIES, INC. (US) | 2007-07-03 | — | — | US | disclosed |
| US-20070001011-A1 | Product packaging including digital data | VERIFICATION TECHNOLOGIES, INC. (US) | 2007-01-04 | — | — | US | disclosed |
| US-7124944-B2 | Product packaging including digital data | VERIFICATION TECHNOLOGIES, INC. (US) | 2006-10-24 | — | — | US | disclosed |
| EP-1200932-B1 | AUTHENTICATION DEVICE AND METHOD OF AUTHENTICATING PRODUCTS OR PRODUCT PACKAGING | SUN CHEMICAL BV (NL) | 2006-09-13 | — | — | EP | disclosed |
| US-7079230-B1 | Portable authentication device and method of authenticating products or product packaging | SUN CHEMICAL B.V. (NL) | 2006-07-18 | — | — | US | disclosed |
| US-20050243305-A1 | Tamper-resistant authentication mark for use in product or product packaging authentication | VIG RAKESH | 2005-11-03 | — | — | US | disclosed |
| US-20050153128-A1 | Product packaging including digital data | SELINFREUND RICHARD H (US) | 2005-07-14 | — | — | US | disclosed |
| US-20040023397-A1 | Tamper-resistant authentication mark for use in product or product packaging authentication | VERIFICATION TECHNOLOGIES, INC. | 2004-02-05 | — | — | US | disclosed |
| US-20040000787-A1 | Authentication mark for a product or product package | SUN CHEMICAL B.V. (AN) | 2004-01-01 | — | — | US | disclosed |
| US-20030112423-A1 | On-line verification of an authentication mark applied to products or product packaging | VERIFICATION TECHNOLOGIES, INC. | 2003-06-19 | — | — | US | disclosed |
| US-20030047610-A1 | Product packaging including digital data | SPENCER TRASK | 2003-03-13 | — | — | US | disclosed |
| US-5541633-A | Ink jet printing of concealed images on carbonless paper | XEROX CORPORATION (US) | 1996-07-30 | — | — | US | disclosed |
| US-5286286-A | Containing diethylene glycol monobutyl ether, glycerol, and a dansyl or porphyrin chromophores | XEROX CORPORATION (US) | 1994-02-15 | — | — | US | disclosed |
| US-5256193-A | Porphyrin chromophore and dendrimer ink composition | XEROX CORPORATION (US) | 1993-10-26 | — | — | US | disclosed |