Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | TERT | O14746 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | TOP1 | P11387 | 3/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | CYCS | P99999 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29965184 | 1.00 | ENPP2 (0.52) | ENPP2TERTALDH1A1MAPTKDM4E | |
| SCHEMBL4141501 | 1.00 | ENPP2 (0.52) | ENPP2TERTALDH1A1MAPTKDM4E | |
| SCHEMBL4147314 | 0.87 | ENPP2 (0.49) | ENPP2TERTALDH1A1MAPTKDM4E | |
| SCHEMBL4145137 | 0.85 | ENPP2 (0.46) | ENPP2TERTALDH1A1MAPTKDM4E | |
| SCHEMBL30417480 | 0.85 | TERT (0.43) | ENPP2TERTTOP1CYCS | |
| SCHEMBL18418 | 0.84 | TERT (0.44) | ENPP2TERTTOP1CYCS | |
| Trifluoromethanesulfonic Acid SCHEMBL4126859 | 0.84 | ENPP2 (0.41) | ENPP2TERTTOP1ABCG2CYCS | |
| SCHEMBL4134381 | 0.83 | ENPP2 (0.46) | ENPP2TERTALDH1A1MAPTKDM4E | |
| Bromide SCHEMBL4128664 | 0.83 | TERT (0.43) | ENPP2TERTTOP1CYCS | |
| Hydrochloric Acid SCHEMBL7246124 | 0.83 | TERT (0.43) | ENPP2TERTTOP1CYCS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050090428-A1 | Porphyrins with virucidal activity | EMORY UNIVERSITY (US) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090428-A1 | Porphyrins with virucidal activity | ZP1, MAVS, VIP | ENPP2 3021/4885TERT 869/4885ALDH1A1 3022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.