Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4132659 | 0.86 | NAMPT (0.39) | NAMPTPTGER2LMNAALDH1A1KMT2A | |
| SCHEMBL3782033 | 0.84 | NAMPT (0.37) | GPBAR1NAMPTPTGER2LMNAALDH1A1 | |
| SCHEMBL3654305 | 0.84 | GPBAR1 (0.35) | GPBAR1NAMPTPTGER2CYP1A2CYP3A4 | |
| SCHEMBL4130745 | 0.83 | GPBAR1 (0.40) | GPBAR1NAMPTPTGER2LMNAALDH1A1 | |
| SCHEMBL3654310 | 0.83 | GPBAR1 (0.34) | GPBAR1NAMPTPTGER2SLC22A12CYP1A2 | |
| SCHEMBL4127140 | 0.82 | NAMPT (0.33) | NAMPTLMNAALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4130844 | 0.82 | CYP1A2 (0.39) | GPBAR1SLC22A12CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL4130696 | 0.82 | SLC22A12 (0.36) | GPBAR1NAMPTSLC22A12CYP1A2CYP3A4 | |
| SCHEMBL4125901 | 0.78 | NAMPT (0.35) | NAMPTALDH1A1 | |
| SCHEMBL4138201 | 0.77 | GPBAR1 (0.37) | GPBAR1NAMPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-B1 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2014-12-31 | — | — | EP | disclosed |
| US-20090156642-A1 | 5-Membered heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156642-A1 | 5-Membered heterocyclic compound | CEL, PGA5, COG5 | GPBAR1 52/4885NAMPT 2129/4885PTGER2 1424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.