SCHEMBL4130771 — predicted protein targets

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	ALDH1A1	P00352	1/20	0.42

▸	SMN1; SMN2	Q16637	1/20	0.42

▸	FFAR4	Q5NUL3	12/20	0.39

▸	LMNA	P02545	1/20	0.39

▸	HRH3	Q9Y5N1	3/20	0.35

▸	ABCB1	P08183	1/20	0.35

▸	RORC	P51449	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4135822	0.83	ALDH1A1 (0.45)	ALDH1A1FFAR4
SCHEMBL4136516	0.81	HRH3 (0.47)	FFAR4HRH3
SCHEMBL4123180	0.79	HRH3 (0.39)	ALDH1A1FFAR4HRH3
SCHEMBL4141352	0.78	FFAR4 (0.48)	ALDH1A1FFAR4HRH3
SCHEMBL4130768	0.77	ALDH1A1 (0.49)	ALDH1A1SMN1; SMN2LMNA
SCHEMBL4135581	0.74	TLR9 (0.38)	FFAR4HRH3
SCHEMBL4140027	0.74	HRH3 (0.45)	ALDH1A1SMN1; SMN2FFAR4HRH3
SCHEMBL4140025	0.72	SCD (0.40)	LMNAHRH3
SCHEMBL5023862	0.72	ALDH1A1 (0.45)	ALDH1A1SMN1; SMN2LMNA
SCHEMBL13262205	0.71	ABCB1 (0.43)	ALDH1A1SMN1; SMN2ABCB1RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2021004-A2	SUBSTITUTED AZASPIRO DERIVATIVES	NEUROGEN CORPORATION (US)	2009-02-11	—	—	EP	claimed
WO-2007133561-A2	SUBSTITUTED AZASPIRO DERIVATIVES	NEUROGEN CORPORATION (US)	2007-11-22	—	—	WO	claimed