Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Pseudoephedrine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | GMNN | O75496 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.81 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.81 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.81 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.81 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.81 |
| ▸ | RGS12 | O14924 | 1/20 | 0.81 |
| ▸ | GLA | P06280 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Racephedrine SCHEMBL10995708 | 1.00 | ALDH1A1 (1.00) | ALDH1A1LMNAKDM4EKMT2ANPSR1 | |
| Ephedrine SCHEMBL41262 | 1.00 | ALDH1A1 (1.00) | ALDH1A1LMNAKDM4EKMT2ANPSR1 | |
| Ephedrine SCHEMBL547932 | 1.00 | ALDH1A1 (1.00) | ALDH1A1LMNAKDM4EKMT2ANPSR1 | |
| Racephedrine SCHEMBL41264 | 1.00 | ALDH1A1 (1.00) | ALDH1A1LMNAKDM4EKMT2ANPSR1 | |
| Racephedrine SCHEMBL41263 | 1.00 | ALDH1A1 (1.00) | ALDH1A1LMNAKDM4EKMT2ANPSR1 | |
| Pseudoephedrine SCHEMBL41309 | 1.00 | ALDH1A1 (1.00) | ALDH1A1LMNAKDM4EKMT2ANPSR1 | |
| Pseudoephedrine SCHEMBL6229122 | 0.98 | ALDH1A1 (0.96) | ALDH1A1LMNAKDM4EKMT2ANPSR1 | |
| Racephedrine SCHEMBL6229123 | 0.98 | ALDH1A1 (0.96) | ALDH1A1LMNAKDM4EKMT2ANPSR1 | |
| Racephedrine SCHEMBL28900784 | 0.98 | ALDH1A1 (0.96) | ALDH1A1LMNAKDM4EKMT2ANPSR1 | |
| Ephedrine SCHEMBL4785 | 0.90 | CYP2D6 (1.00) | ALDH1A1LMNAKDM4EKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1719 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724049-A1 | MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF | Catalent Ontario Limited (CA) | 2026-04-15 | — | — | EP | claimed |
| US-20250241824-A1 | CHILD-PROOF STICK PACK | BAYER HEALTHCARE LLC | 2025-07-31 | — | — | US | claimed |
| EP-4496754-A1 | CHILD-PROOF STICK PACK | Bayer Healthcare LLC (US) | 2025-01-29 | — | — | EP | claimed |
| WO-2024254056-A1 | MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF | CATALENT ONTARIO LIMITED (CA) | 2024-12-12 | — | — | WO | claimed |
| CN-118946505-A | Child resistant stick pack | 拜耳医药保健有限责任公司 | 2024-11-12 | — | — | CN | claimed |
| US-20240282425-A1 | AUTHENTICATION METHODS AND SYSTEMS FOR DISPENSED PRESCRIPTIONS | LOW GORDON KEITH (US) | 2024-08-22 | — | — | US | claimed |
| US-20240189227-A1 | EASY CHEW FORMULATIONS | HALEON US HOLDINGS LLC | 2024-06-13 | — | — | US | claimed |
| EP-4333895-A1 | EASY CHEW FORMULATIONS | Haleon US IP LLC (US) | 2024-03-13 | — | — | EP | claimed |
| CN-117255696-A | Chewable formulation | 葛兰素史克消费保健（美国）控股有限责任公司 | 2023-12-19 | — | — | CN | claimed |
| WO-2023183424-A1 | CHILD-PROOF STICK PACK | BAYER HEALTHCARE LLC (US) | 2023-09-28 | — | — | WO | claimed |
| EP-0421581-A1 | Chewable spray dried spheroidal microcapsules and wax coated microcapsules and methods for preparing same | WARNER-LAMBERT COMPANY (US) | 1991-04-10 | — | — | EP | claimed |
| EP-0421582-A1 | Chewable spray dried spheroidal microcapsules and polymer coated microcapsules and method for preparing same | WARNER-LAMBERT COMPANY (US) | 1991-04-10 | — | — | EP | claimed |
| US-4990535-A | Sustained release tablet | SCHERING CORPORATION (US) | 1991-02-05 | — | — | US | claimed |
| WO-1990013295-A1 | PHARMACEUTICAL COMPOSITION COMPRISING LORATADINE, IBUPROFEN AND PSEUDOEPHEDRINE | SCHERING CORPORATION (US) | 1990-11-15 | — | — | WO | claimed |
| EP-0396404-A1 | Pharmaceutical composition comprising loratadine, ibuprofen and pseudoephedrine | SCHERING CORPORATION (US) | 1990-11-07 | — | — | EP | claimed |
| EP-0351897-A2 | Skin penetration system for salts of amine-functional drugs | THE PROCTER & GAMBLE COMPANY (US) | 1990-01-24 | — | — | EP | claimed |
| US-4777050-A | IN CELLULOSE POLYMER MATRIX | SCHERING CORPORATION (US) | 1988-10-11 | — | — | US | claimed |
| US-4695591-A | Controlled release dosage forms comprising hydroxypropylmethylcellulose | SCHERING CORPORATION (US) | 1987-09-22 | — | — | US | claimed |
| US-4657757-A | Controlled release dosage form comprising acetaminophen, pseudoephedrine sulfate and dexbrompheniramine maleate | SCHERING CORPORATION (US) | 1987-04-14 | — | — | US | claimed |
| US-4601894-A | ANALGLE0ICS | SCHERING CORPORATION (US) | 1986-07-22 | — | — | US | claimed |