Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 3/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4126682 | 0.84 | ALDH1A1 (0.49) | CYP2C19CPA1MAPTTDP1L3MBTL1 | |
| SCHEMBL4111932 | 0.81 | MAOB (0.53) | L3MBTL1MRGPRX4SMN1; SMN2 | |
| SCHEMBL4125403 | 0.80 | ALDH1A1 (0.60) | CYP19A1CYP2C19MAPTMEN1KMT2A | |
| SCHEMBL22831440 | 0.77 | NPSR1 (0.50) | CYP2C19CYP1A2CPA1MAPTKMT2A | |
| SCHEMBL4120406 | 0.75 | ALDH1A1 (0.45) | CYP2C19MAPTMEN1KMT2ATDP1 | |
| SCHEMBL2628014 | 0.74 | CPA1 (0.45) | CYP2C19CYP3A4CPA1MAPTMEN1 | |
| SCHEMBL4111632 | 0.74 | CPA1 (0.45) | CYP2C19CYP3A4CPA1MAPTMEN1 | |
| SCHEMBL222290 | 0.73 | NPSR1 (0.48) | CYP2C19CPA1MAPTMEN1KMT2A | |
| SCHEMBL222291 | 0.73 | NPSR1 (0.48) | CYP2C19CPA1MAPTMEN1KMT2A | |
| SCHEMBL16785486 | 0.73 | ALDH1A1 (0.64) | CYP2C19MAPTTDP1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8084641-B2 | Organocataslysts and methods of use in chemical synthesis | STC.UNM (US) | 2011-12-27 | — | — | US | disclosed |
| US-8084641-B2 | Organocataslysts and methods of use in chemical synthesis | STC.UNM (US) | 2011-12-27 | — | — | US | disclosed |
| US-20090088588-A1 | Organocatalysts and methods of use in chemical synthesis | REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2009-04-02 | — | — | US | disclosed |
| US-20090088588-A1 | Organocatalysts and methods of use in chemical synthesis | REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088588-A1 | Organocatalysts and methods of use in chemical synthesis | ICMT, PPOX, CYP4F3 | BRD4 3402/4885CYP19A1 121/4885SGMS2 2918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.