SCHEMBL4132067

SCHEMBL4132067

c1nc2cc3sccc3cc2o1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 3/20 0.39
CHRNB2 P17787 1/20 0.35
CHRNA4 P43681 1/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP2A6 P11509 2/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
CTNNB1 P35222 1/20 0.32
WNT3A P56704 1/20 0.32
GRM4 Q14833 2/20 0.32
PTPRC P08575 1/20 0.31
PTPN6 P29350 1/20 0.31
PTPN11 Q06124 1/20 0.31
PTPN22 Q9Y2R2 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4143120 0.93 DYRK1A (0.39) DYRK1ACHRNB2CHRNA4MEN1ALDH1A1
SCHEMBL941915 0.76 CHRNB2 (0.48) DYRK1ACHRNB2CHRNA4MEN1ALDH1A1
SCHEMBL4137601 0.72 DYRK1A (0.42) DYRK1ACHRNB2CHRNA4MEN1ALDH1A1
SCHEMBL18710589 0.72 ALDH1A1 (0.38) DYRK1ACHRNB2CHRNA4MEN1ALDH1A1
Benzo[D]Oxazole SCHEMBL6012058 0.71 ALDH1A1 (0.35) DYRK1AALDH1A1GAANPC1RAB9A
SCHEMBL7786914 0.71 DYRK1A (0.39) DYRK1AMEN1ALDH1A1GAAKMT2A
SCHEMBL1156058 0.71 NQO2 (0.50) DYRK1ACHRNB2CHRNA4MEN1ALDH1A1
SCHEMBL6119475 0.69 CHRNB2 (0.47) DYRK1ACHRNB2CHRNA4MEN1ALDH1A1
SCHEMBL164774 0.68 CYP2A6 (0.50) DYRK1AMEN1ALDH1A1KMT2ACYP2A6
SCHEMBL15834699 0.68 DYRK1A (0.42) DYRK1AMEN1ALDH1A1KMT2ACYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160197275-A1 EMITTER HAVING A CONDENSED RING SYSTEM MERCK PATENT GMBH (DE) 2016-07-07 US disclosed
US-20160197275-A1 EMITTER HAVING A CONDENSED RING SYSTEM MERCK PATENT GMBH (DE) 2016-07-07 US disclosed
WO-2014094965-A2 EMITTER HAVING A CONDENSED RING SYSTEM MERCK PATENT GMBH (DE) 2014-06-26 WO disclosed
US-20090092766-A1 GRAFT PATTERN FORMING METHOD AND CONDUCTIVE PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2009-04-09 US disclosed
WO-2006123834-A2 GRAFT PATTERN FORMING METHOD AND CONDUCTIVE PATTERN FORMING METHOD FUJIFILM CORPORATION (JP) 2006-11-23 WO disclosed
EP-1061411-B1 Silver halide photographic emulsion and photographic light-sensitive material using the same FUJI PHOTO FILM CO LTD (JP) 2006-10-11 EP disclosed
EP-1067430-B1 Silver halide photographic emulsion and photographic light-sensitive material using the same FUJI PHOTO FILM CO LTD (JP) 2006-09-13 EP disclosed
US-20050271987-A1 Silver halide photographic emulsion and photographic light-sensitive material using the same FUJI PHOTO FILM CO., LTD. 2005-12-08 US disclosed
US-6838231-B2 Production process of silver halide photographic emulsion and silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2005-01-04 US disclosed
US-20040166450-A1 Silver halide photographic emulsion and photographic light-sensitive material using the same FUJI PHOTO FILM CO., LTD. 2004-08-26 US disclosed
US-20030180673-A1 Production process of silver halide photographic emulsion and silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. 2003-09-25 US disclosed
US-20030170575-A1 Silver halide photographic material FUJI PHOTO FILM CO., LTD. 2003-09-11 US disclosed
US-6610466-B2 Exhibits increased light absorption and light absorption intensity and which has sensitizing dyes adsorbed in multilayer form stably even in the presence of an organic solvent. FUJI PHOTO FILM CO., LTD. (JP) 2003-08-26 US disclosed
US-6582894-B1 Silver haide photographic emulsion and photographic light-sensitive material using same FUJI PHOTO FILM CO., LTD. (JP) 2003-06-24 US disclosed
US-6521401-B1 Spectrally sensitizing with dye that does not have electric charge or forms an inner salt FUJI PHOTO FILM CO., LTD. (JP) 2003-02-18 US disclosed
US-20020177087-A1 Silver halide photographic lightsensitive material FUJIFILM CORPORATION (JP) 2002-11-28 US disclosed
US-6465166-B1 HIGH SPEED SILVER HALIDE PHOTOGRAPHIC EMULSION WHEREIN THE GRAIN AGGLOMERATION IS PREVENTED AND PHOTOGRAPHIC MATERIAL REDUCED IN RESIDUAL DYE COLOR AFTER PROCESSING FUJI PHOTO FILM. CO., LTD. (JP) 2002-10-15 US disclosed
US-20020012892-A1 Methine compound-containing silver halide photographic emulsion and photographic material using the same FUJIFILM CORPORATION (JP) 2002-01-31 US disclosed
EP-1067430-A1 Silver halide photographic emulsion and photographic light-sensitive material using the same FUJI PHOTO FILM CO., LTD. (JP) 2001-01-10 EP disclosed
EP-1061411-A1 Silver halide photographic emulsion and photographic light-sensitive material using the same FUJI PHOTO FILM CO., LTD. (JP) 2000-12-20 EP disclosed