Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.31 |
| ▸ | LIPC | P11150 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3646705 | 0.85 | KDM4E (0.32) | HCAR2ESR1 | |
| SCHEMBL4130273 | 0.83 | FEN1 (0.33) | ESR1 | |
| SCHEMBL4135456 | 0.83 | NAMPT (0.33) | ESR1 | |
| SCHEMBL4119121 | 0.81 | NFE2L2 (0.33) | — | |
| SCHEMBL4126014 | 0.81 | NAMPT (0.34) | — | |
| Fumaric Acid SCHEMBL4132147 | 0.80 | CYP2A6 (0.35) | LIPGLIPC | |
| Fumaric Acid SCHEMBL4132143 | 0.80 | CYP2A6 (0.35) | LIPGLIPC | |
| SCHEMBL3651800 | 0.77 | NAMPT (0.35) | — | |
| Fumaric Acid SCHEMBL3695553 | 0.76 | CYP2A6 (0.32) | LIPGLIPC | |
| SCHEMBL3651793 | 0.74 | NAMPT (0.33) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-B1 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2014-12-31 | — | — | EP | disclosed |
| US-20090156642-A1 | 5-Membered heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156642-A1 | 5-Membered heterocyclic compound | CEL, PGA5, COG5 | HCAR2 339/4885ESR1 3418/4885LIPG 2467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.