Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | YAP1 | P46937 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4126334 | 0.92 | ACHE (0.36) | GPR119JAK2JAK1ACHE | |
| SCHEMBL4119099 | 0.87 | GPR119 (0.38) | GPR119ACHEYAP1FAAH | |
| SCHEMBL4126974 | 0.87 | GPR119 (0.40) | GPR119ACHEFAAH | |
| SCHEMBL13596559 | 0.87 | GPR119 (0.42) | GPR119ACHEYAP1FAAH | |
| SCHEMBL4122100 | 0.86 | GPR119 (0.37) | GPR119ACHEFAAH | |
| SCHEMBL4122083 | 0.84 | FAAH (0.40) | GPR119CSF1RACHEKDRFAAH | |
| SCHEMBL4132982 | 0.83 | GPR119 (0.38) | GPR119JAK2JAK1CSF1RYAP1 | |
| SCHEMBL4120919 | 0.82 | GPR119 (0.44) | GPR119ACHEYAP1FAAH | |
| SCHEMBL4119841 | 0.82 | ACHE (0.38) | GPR119JAK2JAK1ACHE | |
| SCHEMBL4122307 | 0.81 | GPR119 (0.43) | GPR119ACHEYAP1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
| EP-2017275-A1 | BENZISOXAZOLE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2009-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | NR1I2, NR1I3, NR0B1 | GPR119 122/4885JAK2 1131/4885JAK1 1650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.