Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ROR1 | Q01973 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12375248 | 0.95 | CYP3A4 (0.51) | CYP3A4SMN1; SMN2USP2MAPK1KMT2A | |
| SCHEMBL26481059 | 0.91 | CYP3A4 (0.54) | CYP3A4SMN1; SMN2USP2MAPK1KMT2A | |
| SCHEMBL30792317 | 0.90 | CYP3A4 (0.58) | CYP3A4SMN1; SMN2USP2MAPK1KMT2A | |
| SCHEMBL656327 | 0.90 | CYP3A4 (0.58) | CYP3A4SMN1; SMN2USP2MAPK1KMT2A | |
| SCHEMBL28652556 | 0.89 | CYP3A4 (0.41) | CYP3A4SMN1; SMN2USP2MAPK1KMT2A | |
| SCHEMBL23327124 | 0.88 | CYP3A4 (0.60) | CYP3A4SMN1; SMN2USP2MAPK1KMT2A | |
| SCHEMBL30545309 | 0.88 | CYP3A4 (0.60) | CYP3A4SMN1; SMN2USP2MAPK1KMT2A | |
| SCHEMBL16166347 | 0.88 | TP53 (0.45) | CYP3A4MAPK1KMT2AMAPTKDM4E | |
| SCHEMBL31415699 | 0.88 | TP53 (0.45) | CYP3A4MAPK1KMT2AMAPTKDM4E | |
| SCHEMBL23804635 | 0.85 | CYP3A4 (0.45) | CYP3A4SMN1; SMN2USP2MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11643405-B2 | Compound for treatment or prevention of liver diseases | JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO., LTD. (CN) | 2023-05-09 | — | — | US | disclosed |
| US-11643405-B2 | Compound for treatment or prevention of liver diseases | JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO., LTD. (CN) | 2023-05-09 | — | — | US | disclosed |
| CN-110294732-B | Pharmaceutical compound for treating liver diseases and application thereof | 江苏新元素医药科技有限公司 | 2021-10-26 | — | — | CN | disclosed |
| US-20210246126-A1 | COMPOUND FOR TREATMENT OR PREVENTION OF LIVER DISEASES | JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO., LTD. (CN) | 2021-08-12 | — | — | US | disclosed |
| EP-3805216-A1 | COMPOUNDS FOR TREATMENT OR PREVENTION OF LIVER DISEASES | Jiangsu Atom Bioscience and Pharmaceutical Co., Ltd. (CN) | 2021-04-14 | — | — | EP | disclosed |
| US-10450292-B2 | Inhibitors of bacterial RNA polymerase: arylpropanoyl, arylpropenoyl, and arylcyclopropanecarboxyl phloroglucinols | Rutgers, The State University of New Jersesy (US) | 2019-10-22 | — | — | US | disclosed |
| US-20190023682-A1 | INHIBITORS OF BACTERIAL RNA POLYMERASE: ARYLPROPANOYL, ARYLPROPENOYL, AND ARYLCYCLOPROPANECARBOXYL PHLOROGLUCINOLS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2019-01-24 | — | — | US | disclosed |
| WO-2017100645-A2 | INHIBITORS OF BACTERIAL RNA POLYMERASE: ARYLPROPANOYL, ARYLPROPENOYL, AND ARYLCYCLOPROPANECARBOXYL PHLOROGLUCINOLS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-06-15 | — | — | WO | disclosed |
| WO-2017100645-A2 | INHIBITORS OF BACTERIAL RNA POLYMERASE: ARYLPROPANOYL, ARYLPROPENOYL, AND ARYLCYCLOPROPANECARBOXYL PHLOROGLUCINOLS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-06-15 | — | — | WO | disclosed |
| US-20090092624-A1 | Antiinfective Flavononol Compounds and Methods of Use Thereof | HERBALSCIENCE GROUP, LLC | 2009-04-09 | — | — | US | disclosed |
| WO-2001007034-A1 | MULTIDRUG RESISTANCE PUMP INHIBITORS AND USES THEREOF | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2001-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210246126-A1 | COMPOUND FOR TREATMENT OR PREVENTION OF LIVER DISEASES | SLC10A1, GYS2, CPT1A | CYP3A4 187/4885SMN1; SMN2 2676/4885USP2 4095/4885 |
| US-20190023682-A1 | INHIBITORS OF BACTERIAL RNA POLYMERASE: ARYLPROPANOYL, ARYLPROPENOYL, AND ARYLCYCLOPROPANECARBOXYL PHLOROGLUCINOLS | RNGTT, ELL, PGLS | CYP3A4 2495/4885SMN1; SMN2 4815/4885USP2 1776/4885 |
| US-20090092624-A1 | Antiinfective Flavononol Compounds and Methods of Use Thereof | MPO, VIP, FABP2 | CYP3A4 385/4885SMN1; SMN2 4160/4885USP2 2432/4885 |
| US-10450292-B2 | Inhibitors of bacterial RNA polymerase: arylpropanoyl, arylpropenoyl, and arylcyclopropanecarboxyl phloroglucinols | RNGTT, ELL, PGLS | CYP3A4 2495/4885SMN1; SMN2 4815/4885USP2 1776/4885 |
| US-11643405-B2 | Compound for treatment or prevention of liver diseases | SLC10A1, GYS2, CPT1A | CYP3A4 187/4885SMN1; SMN2 2676/4885USP2 4095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.