Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | LPL | P06858 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394300 | 0.87 | TAAR1 (0.76) | TAAR1TSHRMAPTKDM4ENPC1 | |
| Pyridine SCHEMBL29022751 | 0.87 | KDM4E (0.54) | TAAR1TSHRMAPTKDM4ENPC1 | |
| SCHEMBL30487922 | 0.85 | TAAR1 (0.73) | TAAR1TSHRMAPTKDM4ENPC1 | |
| SCHEMBL244155 | 0.79 | — | — | |
| SCHEMBL19661647 | 0.79 | TAAR1 (0.48) | TAAR1TSHRMAPTKDM4ENPC1 | |
| SCHEMBL19662294 | 0.79 | TAAR1 (0.48) | TAAR1TSHRMAPTKDM4ENPC1 | |
| SCHEMBL3249633 | 0.78 | RAB9A (0.62) | TAAR1TSHRMAPTKDM4ENPC1 | |
| SCHEMBL7404185 | 0.78 | TAAR1 (0.64) | TAAR1TSHRMAPTKDM4ENPC1 | |
| SCHEMBL28323221 | 0.77 | TAAR1 (0.62) | TAAR1TSHRMAPTKDM4ENPC1 | |
| SCHEMBL162083 | 0.77 | TAAR1 (0.62) | TAAR1TSHRMAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634400-B2 | Micheliolide derivatives, methods for their preparation and their use as anticancer and antiinflammatory agents | UNIVERSITY OF ROCHESTER (US) | 2023-04-25 | — | — | US | claimed |
| US-20200277270-A1 | MICHELIOLIDE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR USE AS ANTICANCER AND ANTIINFLAMMATORY AGENTS | UNIVERSITY OF ROCHESTER | 2020-09-03 | — | — | US | claimed |
| WO-2019040335-A1 | MICHELIOLIDE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR USE AS ANTICANCER AND ANTIINFLAMMATORY AGENTS | UNIVERSITY OF ROCHESTER (US) | 2019-02-28 | — | — | WO | claimed |
| CN-105209449-B | Inhibitors of the kynurenine pathway | 库拉德夫制药私人有限公司 | 2019-02-01 | — | — | CN | claimed |
| US-20160115508-A1 | PARTHENOLIDE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR USE AS ANTICANCER AGENTS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2016-04-28 | — | — | US | claimed |
| EP-3003317-A2 | PARTHENOLIDE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR USE AS ANTICANCER AGENTS | University Of Rochester (US) | 2016-04-13 | — | — | EP | claimed |
| WO-2014197591-A2 | PARTHENOLIDE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR USE AS ANTICANCER AGENTS | UNIVERSITY OF ROCHESTER (US) | 2014-12-11 | — | — | WO | claimed |
| CN-119708016-A | Cover layer material and high color gamut organic electroluminescent device | 京东方科技集团股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| WO-2023224579-A1 | BISMUTHENE AS A VERSATILE PHOTOCATALYST OPERATING UNDER VARIABLE CONDITIONS FOR THE PHOTOREDOX C–H BOND FUNCTIONALIZATION | KOC UNIVERSITESI (TR) | 2023-11-23 | — | — | WO | disclosed |
| CN-116332962-A | Arylamine compound and display substrate | 京东方科技集团股份有限公司 | 2023-06-27 | — | — | CN | disclosed |
| US-11634400-B2 | Micheliolide derivatives, methods for their preparation and their use as anticancer and antiinflammatory agents | UNIVERSITY OF ROCHESTER (US) | 2023-04-25 | — | — | US | disclosed |
| US-20220306654-A1 | MECHANOREDOX REACTION USING PIEZOELECTRIC MATERIAL, AND PRODUCTION METHOD USING SAID REACTION | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2022-09-29 | — | — | US | disclosed |
| EP-4026821-A1 | MECHANOREDOX REACTION USING PIEZOELECTRIC MATERIAL, AND PRODUCTION METHOD USING SAID REACTION | National University Corporation Hokkaido University (JP) | 2022-07-13 | — | — | EP | disclosed |
| WO-2008040669-A2 | NOVEL INTERMEDIATES FOR THE PREPARATION OF A GLYT1 INHIBITOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-04-10 | — | — | WO | disclosed |
| WO-2008040669-A2 | NOVEL INTERMEDIATES FOR THE PREPARATION OF A GLYT1 INHIBITOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-04-10 | — | — | WO | disclosed |
| CN-1151209-A | Method for detecting nucleic acid and cytoskeleton components by using double-dicationic aryl furan fluorescence | UNIV NORTH CAROLINA CHAPEL HILL (US) | 1997-06-04 | — | — | CN | disclosed |
| WO-1996040997-A1 | METHOD OF FLUORESCENT DETECTION OF NUCLEIC ACIDS AND CYTOSKELETON ELEMENTS USING BIS-DICATIONIC ARYL FURANS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0098629-B1 | ANTI-COAGULANTS OF THE 4-HYDROXYCOUMARIN TYPE, THE PREPARATION THEREOF, AND RODENTICIDAL COMPOSITIONS (BAITS) COMPRISING SUCH ANTI-COAGULANTS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-08-26 | — | — | EP | disclosed |
| US-4520007-A | Anti-coagulants of the 4-hydroxycoumarin type and rodenticidal compositions (baits) comprising such anti-coagulants | SHELL OIL COMPANY (US) | 1985-05-28 | — | — | US | disclosed |
| EP-0098629-A1 | Anti-coagulants of the 4-hydroxycoumarin type, the preparation thereof, and rodenticidal compositions (baits) comprising such anti-coagulants | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306654-A1 | MECHANOREDOX REACTION USING PIEZOELECTRIC MATERIAL, AND PRODUCTION METHOD USING SAID REACTION | PIEZO1, PPOX, TAOK1 | TAAR1 3370/4885TSHR 4009/4885MAPT 4647/4885 |
| US-11634400-B2 | Micheliolide derivatives, methods for their preparation and their use as anticancer and antiinflammatory agents | TNF, C9, CYP51A1 | TAAR1 4609/4885TSHR 4837/4885MAPT 4273/4885 |
| US-20200277270-A1 | MICHELIOLIDE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR USE AS ANTICANCER AND ANTIINFLAMMATORY AGENTS | TNF, C9, CYP51A1 | TAAR1 4609/4885TSHR 4837/4885MAPT 4273/4885 |
| US-20160115508-A1 | PARTHENOLIDE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THEIR USE AS ANTICANCER AGENTS | CYP3A43, POR, CYP3A4 | TAAR1 4846/4885TSHR 4561/4885MAPT 4289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.