Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCPS | Q96C86 | 6/20 | 0.45 |
| ▸ | DHFR | P00374 | 7/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432014 | 0.76 | DCPS (0.51) | DCPSDHFRKCNH2 | |
| SCHEMBL1154558 | 0.75 | DCPS (0.50) | DCPSDHFRKCNH2 | |
| SCHEMBL2165421 | 0.72 | NCF1 (0.49) | DCPSDHFR | |
| SCHEMBL2165907 | 0.72 | DCPS (0.49) | DCPSDHFR | |
| SCHEMBL2165351 | 0.72 | DHFR (0.62) | DCPSDHFR | |
| SCHEMBL12404416 | 0.72 | DCPS (0.48) | DCPSDHFRKCNH2 | |
| SCHEMBL2166082 | 0.71 | DCPS (0.58) | DCPSDHFR | |
| SCHEMBL2167390 | 0.70 | ALDH1A1 (0.64) | DCPSDHFR | |
| SCHEMBL2166066 | 0.70 | ALDH1A1 (0.51) | DCPS | |
| SCHEMBL2166369 | 0.70 | NPSR1 (0.53) | DCPSDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069316-A1 | 2,4-DIAMINOQUINAZOLINES FOR SPINAL MUSCULAR ATROPHY | Families of Spinal Muscular Atrophy (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008016973-A1 | 2,4-DIAMINOQUINAZOLINES FOR SPINAL MUSCULAR ATROPHY | FAMILIES OF SPINAL MUSCULAR ATROPHY (US) | 2008-02-07 | — | — | WO | disclosed |