Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | PDCD1LG2 | Q9BQ51 | 3/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22103746 | 0.90 | POLB (0.55) | POLBGABRA1TSHRGABRB2PDCD1LG2 | |
| SCHEMBL335140 | 0.84 | POLB (0.60) | POLBGABRA1TSHRGABRB2MAPKAPK2 | |
| SCHEMBL7818130 | 0.81 | ADRB2 (0.47) | POLBGABRA1TSHRPDCD1LG2CD274 | |
| SCHEMBL27381281 | 0.81 | POLB (0.66) | POLBGABRA1TSHRGABRB2MAPKAPK2 | |
| SCHEMBL15130966 | 0.80 | OPRM1 (0.67) | POLBGABRA1TSHRGABRB2CYP3A4 | |
| SCHEMBL2985300 | 0.79 | POLB (0.39) | POLBGABRA1TSHRGABRB2PDCD1LG2 | |
| SCHEMBL2986678 | 0.79 | TYR (0.45) | POLBPDCD1LG2CD274 | |
| SCHEMBL18706684 | 0.79 | TSHR (0.52) | POLBGABRA1TSHRGABRB2MAPKAPK2 | |
| SCHEMBL2978324 | 0.79 | POLB (0.39) | POLBTSHRPDCD1LG2CD274CYP3A4 | |
| SCHEMBL11419847 | 0.78 | TSHR (0.41) | POLBGABRA1TSHRGABRB2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090074691-A1 | Topical Delivery System for Antiaging and Skin Whitening Agents | BIODERM RESEARCH (US) | 2009-03-19 | — | — | US | claimed |
| EP-3183967-A1 | PROCESS FOR THE PREPARATION OF A QUELATING AGENT | Trade Corporation International, S.A. Unipersonal (ES) | 2017-06-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090074691-A1 | Topical Delivery System for Antiaging and Skin Whitening Agents | TYR, MMP17, MMP1 | POLB 247/4885GABRA1 4083/4885TSHR 2624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.