Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9908395 | 0.81 | MEN1 (0.51) | MEN1KMT2ANPC1RAB9ACYP1A2 | |
| SCHEMBL13406704 | 0.79 | MEN1 (0.49) | MEN1KMT2ANPC1RAB9ACYP1A2 | |
| SCHEMBL1151811 | 0.77 | MEN1 (0.48) | MEN1KMT2ANPC1RAB9ACYP1A2 | |
| SCHEMBL8402186 | 0.77 | MEN1 (0.48) | MEN1KMT2ANPC1RAB9ACYP1A2 | |
| SCHEMBL13387479 | 0.75 | MEN1 (0.49) | MEN1KMT2ANPC1RAB9AEPHX2 | |
| SCHEMBL13005302 | 0.75 | INPP5A (0.47) | MEN1KMT2ANPC1RAB9ACYP1A2 | |
| SCHEMBL9944396 | 0.72 | HSD17B10 (0.40) | MEN1KMT2ANPC1RAB9ACYP1A2 | |
| SCHEMBL10247711 | 0.70 | MEN1 (0.38) | MEN1KMT2ANPC1RAB9ACYP1A2 | |
| SCHEMBL13998350 | 0.70 | MEN1 (0.38) | MEN1KMT2ANPC1RAB9ACYP1A2 | |
| SCHEMBL1605346 | 0.70 | MEN1 (0.38) | MEN1KMT2ANPC1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090104126-A1 | Sulfamate Compounds and Uses Thereof | SOLVAY PHARMACEUTICALS GMBH (DE) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090104126-A1 | Sulfamate Compounds and Uses Thereof | SULT1A1, SULT1E1, SULT2A1 | MEN1 622/4885KMT2A 1994/4885NPC1 3300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.