Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27772143 | 0.89 | ALDH1A1 (0.40) | ALDH1A1ALOX15NPC1SMN1; SMN2EPHX2 | |
| SCHEMBL9244526 | 0.80 | EPHX2 (0.47) | ALDH1A1ALOX15NPC1SMN1; SMN2EPHX2 | |
| SCHEMBL28931784 | 0.79 | LMNA (0.42) | ALDH1A1NPC1EPHX2MEN1KMT2A | |
| SCHEMBL18135491 | 0.78 | MEN1 (0.43) | ALDH1A1ALOX15NPC1SMN1; SMN2EPHX2 | |
| SCHEMBL8097536 | 0.76 | ALDH1A1 (0.46) | ALDH1A1NPC1SMN1; SMN2EPHX2NPSR1 | |
| SCHEMBL9619395 | 0.76 | ALDH1A1 (0.38) | ALDH1A1ALOX15NPC1SMN1; SMN2EPHX2 | |
| SCHEMBL354415 | 0.76 | SLC22A2 (0.43) | ALDH1A1ALOX15NPC1EPHX2KDM4E | |
| SCHEMBL28524736 | 0.73 | EPHX2 (0.40) | ALDH1A1NPC1SMN1; SMN2EPHX2MEN1 | |
| SCHEMBL6046137 | 0.72 | LCK (0.47) | ALDH1A1EPHX2MEN1KMT2A | |
| SCHEMBL4028622 | 0.72 | ALDH1A1 (0.44) | ALDH1A1ALOX15NPC1SMN1; SMN2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137774-A1 | ADAMANTANE DERIVATIVE, RESIN COMPOSITION CONTAINING SAME, AND OPTOELECTRONIC COMPONENT USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2009-05-28 | — | — | US | disclosed |
| EP-1930327-A1 | ADAMANTANE DERIVATIVE, RESIN COMPOSITION CONTAINING SAME, AND OPTOELECTRONIC COMPONENT USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2008-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137774-A1 | ADAMANTANE DERIVATIVE, RESIN COMPOSITION CONTAINING SAME, AND OPTOELECTRONIC COMPONENT USING SAME | GJA1, CDH1, OR10J3 | ALDH1A1 154/4885ALOX15 39/4885NPC1 2914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.