SCHEMBL413803

SCHEMBL413803

CCCCC(NC=O)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCC)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCCCN)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 7/20 0.56
NPY1R P25929 6/20 0.56
NPY2R P49146 5/20 0.56
OPRK1 P41145 5/20 0.50
NPY5R Q15761 4/20 0.50
NTSR2 O95665 2/20 0.48
NTSR1 P30989 2/20 0.48
ACE P12821 1/20 0.48
OPRM1 P35372 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL413804 1.00 NPY4R (0.56) NPY4RNPY1RNPY2ROPRK1NPY5R
SCHEMBL9197350 0.95 NPY4R (0.62) NPY4RNPY1RNPY2ROPRK1NPY5R
SCHEMBL8213821 0.93 NPY4R (0.56) NPY4RNPY1RNPY2RNPY5RACE
SCHEMBL8213819 0.93 NPY4R (0.56) NPY4RNPY1RNPY2RNPY5RACE
SCHEMBL7033970 0.92 NPY4R (0.57) NPY4RNPY1RNPY2RNPY5RACE
SCHEMBL3649800 0.91 NPY4R (0.67) NPY4RNPY1RNPY2ROPRK1NPY5R
SCHEMBL3649802 0.91 NPY4R (0.67) NPY4RNPY1RNPY2ROPRK1NPY5R
SCHEMBL6565110 0.89 GNPAT (0.53) NPY4RNPY1RNPY2RACE
SCHEMBL8727951 0.86 MME (0.54) NPY4RNPY1RNPY2RACE
SCHEMBL1477244 0.86 MME (0.54) NPY4RNPY1RNPY2RACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3353152-B1 METHOD NORSK MEDISINSK SYKLOTRONSENTER AS (NO) 2021-09-15 EP claimed
US-10869942-B2 Method NORSK MEDISINSK SYKLOTRONSENTER AS (NO) 2020-12-22 US claimed
US-20180311384-A1 METHOD NORSK MEDISINSK SYKLOTRONSENTER AS (NO) 2018-11-01 US claimed
EP-3353152-A1 METHOD Norsk Medisinsk Syklotronsenter AS (NO) 2018-08-01 EP claimed
WO-2017072200-A1 METHOD NORSK MEDISINSK SYKLOTRONSENTER AS (NO) 2017-05-04 WO claimed
US-8530620-B2 Radiolabelling reagents and methods GE HEALTHCARE LIMITED (GB) 2013-09-10 US claimed
EP-2186782-B1 Methods for the purification of radiolabelled products using a solid-support scavanger GE HEALTHCARE LTD (GB) 2013-04-17 EP claimed
EP-2414333-B1 RADIOLABELLING REAGENTS AND METHODS GE HEALTHCARE LTD (GB) 2013-02-13 EP claimed
EP-2414333-A1 RADIOLABELLING REAGENTS AND METHODS GE Healthcare UK Limited (GB) 2012-02-08 EP claimed
US-20120022227-A1 RADIOLABELLING REAGENTS AND METHODS GE HEALTHCARE LIMITED (GB) 2012-01-26 US claimed
WO-2010114723-A1 RADIOLABELLING REAGENTS AND METHODS GE HEALTHCARE LIMITED (GB) 2010-10-07 WO claimed
EP-3353152-B1 METHOD NORSK MEDISINSK SYKLOTRONSENTER AS (NO) 2021-09-15 EP disclosed
US-20210252174-A1 METHOD NORSK MEDISINSK SYKLOTRONSENTER AS (NO) 2021-08-19 US disclosed
US-10869942-B2 Method NORSK MEDISINSK SYKLOTRONSENTER AS (NO) 2020-12-22 US disclosed
US-20180311384-A1 METHOD NORSK MEDISINSK SYKLOTRONSENTER AS (NO) 2018-11-01 US disclosed
EP-0732944-A4 LABELED CHEMOTACTIC PEPTIDES TO IMAGE FOCAL SITES OF INFECTION OR INFLAMMATION GEN HOSPITAL CORP (US) 2000-06-07 EP disclosed
US-5792444-A ADMINISTERING LABELED CHEMOTACTIC PEPTIDE WHICH ACCUMULATES AT SITE OF INFECTION OR INFLAMMATION THE GENERAL HOSPITAL CORPORATION (US) 1998-08-11 US disclosed
CN-1141002-A Labeled chemotactic peptides for imaging of sites of infection or inflammation lesions GEN HOSPITAL CORP (US) 1997-01-22 CN disclosed
EP-0732944-A1 LABELED CHEMOTACTIC PEPTIDES TO IMAGE FOCAL SITES OF INFECTION OR INFLAMMATION THE GENERAL HOSPITAL CORPORATION (US) 1996-09-25 EP disclosed
WO-1995011045-A1 LABELED CHEMOTACTIC PEPTIDES TO IMAGE FOCAL SITES OF INFECTION OR INFLAMMATION THE GENERAL HOSPITAL CORPORATION (US) 1995-04-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10869942-B2 Method MPI, DUT, NT5E NPY4R 656/4885NPY1R 1081/4885NPY2R 840/4885
US-20180311384-A1 METHOD MPI, DUT, NT5E NPY4R 656/4885NPY1R 1081/4885NPY2R 840/4885
US-20210252174-A1 METHOD MPI, DUT, NT5E NPY4R 656/4885NPY1R 1081/4885NPY2R 840/4885
US-20120022227-A1 RADIOLABELLING REAGENTS AND METHODS ANPEP, DNPEP, QRFPR NPY4R 170/4885NPY1R 356/4885NPY2R 390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.