SCHEMBL9197350

CCCC[C@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)O.CCCC[C@H](NC=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	11/20	0.62

▸	NPY1R	P25929	6/20	0.62

▸	NPY2R	P49146	5/20	0.62

▸	NPY5R	Q15761	4/20	0.53

▸	OPRK1	P41145	1/20	0.53

▸	NTSR2	O95665	3/20	0.52

▸	NTSR1	P30989	3/20	0.52

▸	OPRM1	P35372	2/20	0.51

▸	OPRD1	P41143	2/20	0.51

▸	SORT1	Q99523	1/20	0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL413804	0.95	NPY4R (0.56)	NPY4RNPY1RNPY2RNPY5ROPRK1
SCHEMBL413803	0.95	NPY4R (0.56)	NPY4RNPY1RNPY2RNPY5ROPRK1
SCHEMBL3649802	0.94	NPY4R (0.67)	NPY4RNPY1RNPY2RNPY5ROPRK1
SCHEMBL3649800	0.94	NPY4R (0.67)	NPY4RNPY1RNPY2RNPY5ROPRK1
SCHEMBL7033970	0.91	NPY4R (0.57)	NPY4RNPY1RNPY2RNPY5R
SCHEMBL6131648	0.90	OPRK1 (0.60)	NPY4RNPY1RNPY2RNPY5ROPRK1
SCHEMBL6131647	0.90	OPRK1 (0.60)	NPY4RNPY1RNPY2RNPY5ROPRK1
SCHEMBL8213821	0.88	NPY4R (0.56)	NPY4RNPY1RNPY2RNPY5R
SCHEMBL8213819	0.88	NPY4R (0.56)	NPY4RNPY1RNPY2RNPY5R
SCHEMBL2064607	0.88	NPY4R (0.58)	NPY4RNPY1RNPY2RNPY5ROPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0398143-B1	Labeled chemotactic peptides to image focal sites of infection or inflammation	GEN HOSPITAL CORP (US)	1995-03-15	—	—	EP	disclosed