Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.77 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.62 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | TYK2 | P29597 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.58 |
| ▸ | FNTA | P49354 | 1/20 | 0.58 |
| ▸ | FNTB | P49356 | 1/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14688750 | 0.88 | NPC1 (0.63) | HPGDSMN1; SMN2ALDH1A1TYK2POLB | |
| SCHEMBL21993 | 0.87 | HPGD (1.00) | HPGDKCNK3KCNK9SMN1; SMN2ALDH1A1 | |
| SCHEMBL3411986 | 0.86 | HPGD (0.66) | HPGDKCNK3KCNK9SMN1; SMN2ALDH1A1 | |
| SCHEMBL24172126 | 0.84 | PTGS2 (0.70) | HPGDKCNK3KCNK9SMN1; SMN2ALDH1A1 | |
| SCHEMBL7764478 | 0.84 | HPGD (0.74) | HPGDKCNK3KCNK9SMN1; SMN2ALDH1A1 | |
| SCHEMBL28994974 | 0.84 | HPGD (0.74) | HPGDKCNK3KCNK9SMN1; SMN2ALDH1A1 | |
| Iodomethane SCHEMBL20530190 | 0.84 | HPGD (0.93) | HPGDKCNK3KCNK9SMN1; SMN2ALDH1A1 | |
| SCHEMBL22720100 | 0.83 | HPGD (0.72) | HPGDKCNK3KCNK9SMN1; SMN2ALDH1A1 | |
| SCHEMBL18190481 | 0.83 | MEN1 (0.72) | HPGDKCNK3KCNK9SMN1; SMN2ALDH1A1 | |
| SCHEMBL28652342 | 0.82 | HSD17B10 (0.70) | HPGDALDH1A1POLBCRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102203067-B | Hedgehog pathway modulators | IRM LLC | 2014-01-15 | — | — | CN | claimed |
| CN-118019802-A | Resin composition, prepreg, metal foil-clad laminate, resin composite sheet, printed wiring board, and semiconductor device | 三菱瓦斯化学株式会社 | 2024-05-10 | — | — | CN | disclosed |
| CN-118019807-A | Resin composition, prepreg, metal foil-clad laminate, resin composite sheet, printed wiring board, and semiconductor device | 三菱瓦斯化学株式会社 | 2024-05-10 | — | — | CN | disclosed |
| CN-115057794-B | Method for removing methylation of cerium catalytic oxidation amide by visible light induction | 桂林理工大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-110294772-B | 2-alkyl silicon-benzamide compound and synthesis method thereof | 五邑大学 | 2021-12-28 | — | — | CN | disclosed |
| CN-109942461-B | Malononitrile oxime ether compound and its use | 沈阳中化农药化工研发有限公司 | 2020-12-01 | — | — | CN | disclosed |
| CN-110015977-B | Malononitrile oxime ether compound and its use | 沈阳中化农药化工研发有限公司 | 2020-09-15 | — | — | CN | disclosed |
| US-8735384-B2 | Amino heteroaryl compounds as beta-secretase modulators and methods of use | AMGEN INC. (US) | 2014-05-27 | — | — | US | disclosed |
| CN-102203067-B | Hedgehog pathway modulators | IRM LLC | 2014-01-15 | — | — | CN | disclosed |
| US-20130040931-A1 | Amino Heteroaryl Compounds as Beta-Secretase Modulators and Methods of Use | AMGEN INC. (US) | 2013-02-14 | — | — | US | disclosed |
| US-20090131657-A1 | PROCESS FOR ALKENYLATING CARBOXAMIDES | BASF SE (DE) | 2009-05-21 | — | — | US | disclosed |
| CN-1890240-A | Diazabicyclononene derivatives and their use as renin inhibitors | ACTELION PHARMACEUTICALS LTD (CH) | 2007-01-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130040931-A1 | Amino Heteroaryl Compounds as Beta-Secretase Modulators and Methods of Use | BACE1, BACE2, APH1B | HPGD 2637/4885KCNK3 2955/4885KCNK9 3126/4885 |
| US-20090131657-A1 | PROCESS FOR ALKENYLATING CARBOXAMIDES | PRMT5, CYC1, CBR3 | HPGD 3495/4885KCNK3 1488/4885KCNK9 2932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.