Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RGS4 | P49798 | 2/20 | 0.35 |
| ▸ | RGS8 | P57771 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243411 | 0.88 | ALDH1A1 (0.41) | HPGDALDH1A1L3MBTL1TDP1ADRA2A | |
| SCHEMBL1945518 | 0.83 | HPGD (0.55) | HPGDALDH1A1L3MBTL1TDP1ADRA2A | |
| SCHEMBL4148123 | 0.82 | ADRA2A (0.42) | HPGDALDH1A1ADRA2ATSHRMAPT | |
| SCHEMBL2336285 | 0.77 | ALDH1A1 (0.45) | HPGDALDH1A1L3MBTL1TDP1ADRA2A | |
| SCHEMBL5412462 | 0.77 | ALDH1A1 (0.41) | HPGDALDH1A1MAPTPDE4AADORA2A | |
| SCHEMBL1948066 | 0.75 | ADORA2B (0.46) | HPGDALDH1A1L3MBTL1TDP1ADRA2A | |
| SCHEMBL4154718 | 0.74 | ALDH1A1 (0.43) | HPGDALDH1A1MAPTCYP3A4 | |
| SCHEMBL29738657 | 0.72 | ADRA2A (0.45) | HPGDALDH1A1ADRA2ACYP3A4 | |
| SCHEMBL1546589 | 0.72 | HPGD (0.58) | HPGDALDH1A1L3MBTL1PDE4AADORA2A | |
| SCHEMBL7181790 | 0.71 | ADORA2B (0.47) | HPGDALDH1A1ADRA2ATSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090076081-A1 | PIPERIDINE DERIVATIVES AS NK3 ANTAGONISTS | HOFFMANN-LA ROCHE, INC. | 2009-03-19 | — | — | US | disclosed |
| US-20090048374-A1 | STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE | BAERLOCHER GMBH (DE) | 2009-02-19 | — | — | US | disclosed |
| EP-1996649-A1 | STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE | Baerlocher GmbH (DE) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007104379-A1 | STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE | BAERLOCHER GMBH (DE) | 2007-09-20 | — | — | WO | disclosed |
| EP-0041479-B1 | CHLORINE-CONTAINING THERMOPLASTIC POLYMERS STABILIZED WITH AMINO-THIOURACILS | CIBA-GEIGY AG (CH) | 1984-04-04 | — | — | EP | disclosed |
| US-4352903-A | HEAT RESISTANT MOLDING MATERIALS | CIBA-GEIGY CORPORATION (US) | 1982-10-05 | — | — | US | disclosed |
| EP-0041479-A1 | Chlorine-containing thermoplastic polymers stabilized with amino-thiouracils | CIBA-GEIGY AG (CH) | 1981-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076081-A1 | PIPERIDINE DERIVATIVES AS NK3 ANTAGONISTS | DRD2, DRD3, OPRL1 | HPGD 3002/4885ALDH1A1 478/4885L3MBTL1 4409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.