Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RNF114 | Q9Y508 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27623497 | 1.00 | RAB9A (0.38) | RAB9ANPC1RORCMAPTCHRM2 | |
| SCHEMBL4140833 | 0.89 | MEN1 (0.40) | RAB9ANPC1RORCMAPTSLC18A3 | |
| SCHEMBL27623824 | 0.89 | MEN1 (0.40) | RAB9ANPC1RORCMAPTSLC18A3 | |
| SCHEMBL23878309 | 0.87 | HCRTR2 (0.39) | MAPTCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL22039440 | 0.87 | HCRTR2 (0.39) | MAPTCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL23878312 | 0.87 | HCRTR2 (0.39) | MAPTCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7133436 | 0.79 | HCRTR1 (0.49) | CHRM2CHRM1 | |
| SCHEMBL4142002 | 0.79 | HCRTR1 (0.49) | CHRM2CHRM1 | |
| SCHEMBL28397854 | 0.76 | MEN1 (0.40) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL23878277 | 0.76 | MEN1 (0.40) | MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012144-A1 | Optically active 2,5-bisaryl-delta¹ -pyrrolines and their use as pest control agents | PLANT ANDREW | 2009-01-08 | — | — | US | disclosed |
| US-7419936-B2 | Optically active 2,5-bisaryl-Δ1-pyrrolines and their use as pest control agents | BAYER CROPSCIENCE AG (DE) | 2008-09-02 | — | — | US | disclosed |
| CN-1630634-A | Optically active 2,5-bisaryl-delta1-pyrrolines and their use as pest control agents | BAYER CROPSCIENCE AG (DE) | 2005-06-22 | — | — | CN | disclosed |
| US-20040059129-A1 | Optically active 2,5-bisaryl-delta1-pyrrolines and their use as pest control agents | BAYER CROPSCIENCE AG (DE) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012144-A1 | Optically active 2,5-bisaryl-delta¹ -pyrrolines and their use as pest control agents | PLD1, RPS3A, AMY1A | RAB9A 392/4885NPC1 4246/4885RORC 2213/4885 |
| US-20040059129-A1 | Optically active 2,5-bisaryl-delta1-pyrrolines and their use as pest control agents | DDT, CRY1, PLD1 | RAB9A 84/4885NPC1 3907/4885RORC 1351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.