Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 15/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 15/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7133436 | 1.00 | HCRTR1 (0.49) | HCRTR1HCRTR2OPRK1OPRM1CHRM2 | |
| SCHEMBL7138725 | 0.91 | HCRTR1 (0.48) | HCRTR1HCRTR2OPRK1OPRM1CHRM2 | |
| SCHEMBL4135463 | 0.91 | HCRTR1 (0.48) | HCRTR1HCRTR2OPRK1OPRM1CHRM2 | |
| SCHEMBL7138721 | 0.91 | HCRTR1 (0.48) | HCRTR1HCRTR2OPRK1OPRM1CHRM2 | |
| SCHEMBL23878309 | 0.81 | HCRTR2 (0.39) | HCRTR1HCRTR2OPRK1CHRM2CHRM1 | |
| SCHEMBL22039440 | 0.81 | HCRTR2 (0.39) | HCRTR1HCRTR2OPRK1CHRM2CHRM1 | |
| SCHEMBL23878312 | 0.81 | HCRTR2 (0.39) | HCRTR1HCRTR2OPRK1CHRM2CHRM1 | |
| SCHEMBL27623497 | 0.79 | RAB9A (0.38) | CHRM2CHRM1 | |
| SCHEMBL4139541 | 0.79 | RAB9A (0.38) | CHRM2CHRM1 | |
| SCHEMBL6701246 | 0.73 | HCRTR1 (0.46) | HCRTR1HCRTR2CHRM2CHRM1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012144-A1 | Optically active 2,5-bisaryl-delta¹ -pyrrolines and their use as pest control agents | PLANT ANDREW | 2009-01-08 | — | — | US | disclosed |
| US-7419936-B2 | Optically active 2,5-bisaryl-Δ1-pyrrolines and their use as pest control agents | BAYER CROPSCIENCE AG (DE) | 2008-09-02 | — | — | US | disclosed |
| US-20040059129-A1 | Optically active 2,5-bisaryl-delta1-pyrrolines and their use as pest control agents | BAYER CROPSCIENCE AG (DE) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012144-A1 | Optically active 2,5-bisaryl-delta¹ -pyrrolines and their use as pest control agents | PLD1, RPS3A, AMY1A | HCRTR1 1051/4885HCRTR2 2329/4885OPRK1 359/4885 |
| US-20040059129-A1 | Optically active 2,5-bisaryl-delta1-pyrrolines and their use as pest control agents | DDT, CRY1, PLD1 | HCRTR1 525/4885HCRTR2 1235/4885OPRK1 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.