Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 10/20 | 0.67 |
| ▸ | SYK | P43405 | 2/20 | 0.65 |
| ▸ | IGF1R | P08069 | 1/20 | 0.62 |
| ▸ | AURKA | O14965 | 2/20 | 0.58 |
| ▸ | IDH2 | P48735 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4131488 | 0.85 | KDM4E (0.59) | CTSCSYKIDH2KDM4EKDR | |
| SCHEMBL4131075 | 0.85 | CTSC (0.56) | CTSCSYKIDH2 | |
| SCHEMBL3601052 | 0.81 | HDAC3 (0.67) | CTSCAURKAIDH2KDM4EHDAC3 | |
| SCHEMBL30313912 | 0.81 | HDAC3 (0.67) | CTSCAURKAIDH2KDM4EHDAC3 | |
| SCHEMBL25658127 | 0.81 | CTSC (1.00) | CTSCIDH2CTSL | |
| SCHEMBL29816580 | 0.81 | CTSC (1.00) | CTSCIDH2CTSL | |
| SCHEMBL656905 | 0.79 | SYK (1.00) | SYKIGF1RKDR | |
| SCHEMBL787987 | 0.78 | EGFR (0.62) | CTSCIDH2KDR | |
| SCHEMBL655512 | 0.78 | IGF1R (0.75) | SYKIGF1RHDAC3HDAC1HDAC2 | |
| SCHEMBL30847372 | 0.78 | AURKA (0.72) | CTSCSYKAURKAIDH2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170882-A1 | Methods and compositions | CYTOKINETICS, INCORPORATED | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170882-A1 | Methods and compositions | KIF5B, KIF5C, KIF2C | CTSC 2513/4885SYK 4028/4885IGF1R 4345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.