Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 16/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.42 |
| ▸ | MEN1 | O00255 | 14/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.42 |
| ▸ | MAPT | P10636 | 13/20 | 0.42 |
| ▸ | GLA | P06280 | 13/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 11/20 | 0.42 |
| ▸ | GAA | P10253 | 9/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4123873 | 0.85 | HPGD (0.42) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL4132330 | 0.83 | ALDH1A1 (0.40) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL4131065 | 0.74 | ALDH1A1 (0.40) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL1784958 | 0.71 | ALDH1A1 (0.40) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL19139217 | 0.68 | MEN1 (0.44) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL22859762 | 0.67 | ALDH1A1 (0.36) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL22509268 | 0.65 | PDGFRB (0.50) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL12994700 | 0.65 | CACNA1G (0.38) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL17503347 | 0.64 | HRH4 (0.39) | HPGDMEN1KMT2AMAPTKDM4E | |
| SCHEMBL12643213 | 0.63 | KDM4E (0.35) | HPGDALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044013-B1 | PROCESS FOR PRODUCING 2-HYDROXY-4-(METHYLTHIO)BUTYRATE COMPOUNDS AND INTERMEDIATES THEREOF | SUMITOMO CHEMICAL CO (JP) | 2013-05-29 | — | — | EP | disclosed |
| US-20090192328-A1 | PROCESS FOR PRODUCING 2-HYDROXY-4-(METHLTHIO)BUTYRATE COMPOUNDS AND INTERMEDIATES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192328-A1 | PROCESS FOR PRODUCING 2-HYDROXY-4-(METHLTHIO)BUTYRATE COMPOUNDS AND INTERMEDIATES THEREOF | HAO2, BBOX1, HAO1 | HPGD 213/4885ALDH1A1 35/4885MEN1 1652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.