SCHEMBL4140925

SCHEMBL4140925

CCCCCCCCCCNC(=O)N(C)c1ccc(F)cc1F

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.43
CNR2 P34972 2/20 0.43
EPHX2 P34913 1/20 0.43
TRPV1 Q8NER1 1/20 0.41
NAAA Q02083 1/20 0.40
HTT P42858 1/20 0.40
SOAT1 P35610 1/20 0.40
ASAH1 Q13510 1/20 0.40
THRA P10827 1/20 0.40
THRB P10828 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4133486 0.84 NAAA (0.49) EPHX2NAAAHTTASAH1
SCHEMBL4141687 0.81 HDAC11 (0.45) EPHX2NAAAHTTTHRATHRB
SCHEMBL4138962 0.80 GAA (0.42) HTTSOAT1THRATHRB
SCHEMBL4133101 0.79 NAAA (0.43) EPHX2TRPV1NAAAHTT
SCHEMBL27765252 0.77 SOAT1 (0.58) CNR1CNR2EPHX2TRPV1SOAT1
SCHEMBL6544758 0.75 HDAC3 (0.58) CNR1CNR2NAAAHTTL3MBTL1
SCHEMBL27265696 0.73 EPHX2 (0.69) EPHX2HTTSOAT1
SCHEMBL4129794 0.73 EPHX2 (0.69) EPHX2HTTSOAT1
SCHEMBL4137692 0.73 EPHX2 (0.52) EPHX2NAAAHTT
SCHEMBL9508710 0.72 ALDH1A1 (0.50) NAAAHTTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090192192-A1 INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA TOUCH BIONICS LIMITED (GB) 2009-07-30 US disclosed
US-20090192192-A1 INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA TOUCH BIONICS LIMITED (GB) 2009-07-30 US disclosed
US-20090192192-A1 INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA TOUCH BIONICS LIMITED (GB) 2009-07-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090192192-A1 INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA PGLS, TFPI, Q6ZSR9 CNR1 2563/4885CNR2 2632/4885EPHX2 4248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.