Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 4/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4133486 | 0.83 | NAAA (0.49) | ALDH1A1NPC1RAB9ANAAANAMPT | |
| SCHEMBL29709829 | 0.82 | ALDH1A1 (0.67) | ALDH1A1TP53NPC1RAB9ANAAA | |
| SCHEMBL5268847 | 0.82 | NAAA (0.48) | ALDH1A1NPC1RAB9ANAAAEPHX1 | |
| SCHEMBL3200016 | 0.81 | NAAA (0.50) | ALDH1A1NAAANAMPTEPHX1HTT | |
| SCHEMBL4137692 | 0.80 | EPHX2 (0.52) | ALDH1A1NPC1RAB9ANAAANAMPT | |
| Hexane SCHEMBL28333356 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TP53NAAATSHR | |
| SCHEMBL4137357 | 0.79 | NAAA (0.58) | ALDH1A1NPC1RAB9ANAAANAMPT | |
| SCHEMBL7469022 | 0.79 | NAMPT (0.43) | ALDH1A1NPC1RAB9ANAAANAMPT | |
| Decane SCHEMBL28489733 | 0.78 | ALDH1A1 (0.55) | ALDH1A1TP53NPC1RAB9ANAAA | |
| Octane SCHEMBL28482856 | 0.78 | ALDH1A1 (0.55) | ALDH1A1TP53NPC1RAB9ANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296864-B1 | PROCESS FOR PREPARING UREAS | DOWELANCO (US) | 1993-09-15 | — | — | EP | disclosed |
| US-4987233-A | Process for preparing herbicidal ureas and insecticidal carbamates and carbamate derivatives | ELI LILLY AND COMPANY (US) | 1991-01-22 | — | — | US | disclosed |
| EP-0296864-A2 | Process for preparing ureas | DOWELANCO (US) | 1988-12-28 | — | — | EP | disclosed |