SCHEMBL343159

SCHEMBL343159

C/C(C(N)=O)=C(\C)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 2/20 0.50
LDHB P07195 1/20 0.50
LMNA P02545 3/20 0.44
BLM P54132 2/20 0.44
ALOX15 P16050 1/20 0.44
PMP22 Q01453 1/20 0.44
TDP1 Q9NUW8 2/20 0.42
ACHE P22303 1/20 0.38
FFAR3 O14843 1/20 0.38
LCK P06239 1/20 0.38
FYN P06241 1/20 0.38
CRBN Q96SW2 1/20 0.32
ALDH1A1 P00352 1/20 0.31
OR51E2 Q9H255 1/20 0.31
THRB P10828 1/20 0.31
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
PGGT1B P53609 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2999475 1.00 LDHA (0.50) LDHALDHBLMNABLMALOX15
SCHEMBL343160 1.00 LDHA (0.50) LDHALDHBLMNABLMALOX15
SCHEMBL27696587 0.86 LMNA (0.58) LDHALDHBLMNABLMALOX15
SCHEMBL4141273 0.86 LMNA (0.58) LDHALDHBLMNABLMALOX15
SCHEMBL4779556 0.86 LMNA (0.58) LDHALDHBLMNABLMALOX15
SCHEMBL27476647 0.82 LMNA (0.54) LDHALDHBLMNABLMALOX15
SCHEMBL105998 0.82 FFAR3 (0.55) LDHALDHBLMNABLMALOX15
SCHEMBL10661655 0.82 FFAR3 (0.55) LDHALDHBLMNABLMALOX15
SCHEMBL141678 0.82 FFAR3 (0.55) LDHALDHBLMNABLMALOX15
SCHEMBL10661623 0.82 FFAR3 (0.55) LDHALDHBLMNABLMALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1115096-C Water retaining and antifreezing treatment of overwintering grapevine CHINA PETROCHEMICAL CORP (CN) 2003-07-23 CN claimed
CN-1094035-C Grape vine water-retaining antifreezer and its preparation CHINA PETROCHEMICAL CORP (CN) 2002-11-13 CN claimed
CN-1288654-A Water retaining and antifreezing treatment of overwintering grapevine CHINA PETROCHEMICAL CORP (CN) 2001-03-28 CN claimed
US-12543952-B2 Imaging system and method for fluorescence guided surgery THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-02-10 US disclosed
CN-119424371-A ERK2-siRNA nano delivery system, preparation and application thereof in inhibiting vascular intimal hyperplasia 福建医科大学附属第一医院 2025-02-14 CN disclosed
US-20240148912-A1 Activatable Membrane-Interacting Peptides and Methods of Use THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-05-09 US disclosed
CN-116672326-A Size/charge double-conversion nanoparticle-gelatin composite nanocluster and preparation method and application thereof 华南理工大学 2023-09-01 CN disclosed
US-11712483-B2 Activatable membrane-interacting peptides and methods of use THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-08-01 US disclosed
US-11471490-B2 T cells surface-loaded with immunostimulatory fusion molecules and uses thereof TORQUE THERAPEUTICS, INC. (US) 2022-10-18 US disclosed
US-20220175955-A1 PEPTIDE DISPLAY TO ANTIGEN PRESENTING CELLS USING LIPID VEHICLE DANMARKS TEKNISKE UNIVERSITET (DK) 2022-06-09 US disclosed
US-20220008526-A1 METHODS AND COMPOSITIONS FOR CANCER IMMUNOTHERAPY TORQUE THERAPEUTICS, INC. 2022-01-13 US disclosed
EP-1246532-A2 DELIVERY OF SINGLE STRANDED DNA FOR EXPRESSION Mirus Corporation (US) 2002-10-09 EP disclosed
EP-1102785-A1 COMPOSITIONS AND METHODS FOR DRUG DELIVERY USING pH SENSITIVE MOLECULES Mirus Corporation (US) 2001-05-30 EP disclosed
CN-1288654-A Water retaining and antifreezing treatment of overwintering grapevine CHINA PETROCHEMICAL CORP (CN) 2001-03-28 CN disclosed
WO-2000075164-A1 COMPOSITIONS AND METHODS FOR DRUG DELIVERY USING pH SENSITIVE MOLECULES MIRUS CORPORATION (US) 2000-12-14 WO disclosed
WO-2000074635-A2 DELIVERY OF SINGLE STRANDED DNA FOR EXPRESSION MIRUS CORPORATION (US) 2000-12-14 WO disclosed
CN-1233785-A Electrically conductive seamless belt SUMITOMO RUBBER IND (JP) 1999-11-03 CN disclosed
US-4696820-A Photosensitive elements containing polymer of imidylcompounds CIBA-GEIGY CORPORATION (US) 1987-09-29 US disclosed
US-4629773-A PHOTOSENSITIVITY; PHOTOGRAPHIC FILMS; ADHESION CIBA-GEIGY CORPORATION (US) 1986-12-16 US disclosed
US-4532332-A N-(hydroxypolyoxaalkylene)phthalimides and succinimides and acrylate esters thereof CIBA-GEIGY CORPORATION (US) 1985-07-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11712483-B2 Activatable membrane-interacting peptides and methods of use ANXA5, PLA2G2A, F13B LDHA 4089/4885LDHB 3383/4885LMNA 108/4885
US-20240148912-A1 Activatable Membrane-Interacting Peptides and Methods of Use ANXA5, F13B, PLA2G2A LDHA 4069/4885LDHB 3329/4885LMNA 112/4885
US-12543952-B2 Imaging system and method for fluorescence guided surgery FAU, ZKSCAN2, IWS1 LDHA 3675/4885LDHB 3756/4885LMNA 2436/4885
US-20220008526-A1 METHODS AND COMPOSITIONS FOR CANCER IMMUNOTHERAPY ICOS, CD274, TP53 LDHA 1908/4885LDHB 1444/4885LMNA 3226/4885
US-11471490-B2 T cells surface-loaded with immunostimulatory fusion molecules and uses thereof CD4, ICOS, IL2 LDHA 2403/4885LDHB 1546/4885LMNA 4487/4885
US-20220175955-A1 PEPTIDE DISPLAY TO ANTIGEN PRESENTING CELLS USING LIPID VEHICLE CD74, MICA, TAP1 LDHA 3484/4885LDHB 2570/4885LMNA 3463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.