Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4130206 | 0.84 | HSD17B10 (0.52) | SMN1; SMN2MAPTALDH1A1MITFS1PR4 | |
| Dimethylformamide SCHEMBL28746208 | 0.83 | L3MBTL1 (0.45) | SMN1; SMN2MAPTALDH1A1MITFS1PR4 | |
| SCHEMBL5697676 | 0.82 | HSD17B10 (0.56) | SMN1; SMN2MAPTALDH1A1MITFS1PR4 | |
| SCHEMBL4153053 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTALDH1A1MITFS1PR4 | |
| SCHEMBL27628175 | 0.74 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTALDH1A1MITFS1PR4 | |
| SCHEMBL3630523 | 0.73 | ALDH1A1 (0.59) | SMN1; SMN2MAPTALDH1A1NPC1L3MBTL1 | |
| SCHEMBL9373442 | 0.72 | F2 (0.57) | SMN1; SMN2MAPTALDH1A1MITFS1PR4 | |
| SCHEMBL2332678 | 0.72 | LMNA (0.47) | SMN1; SMN2MAPTALDH1A1RAB9AKMT2A | |
| SCHEMBL14267025 | 0.72 | GAA (0.43) | SMN1; SMN2MAPTALDH1A1MITFS1PR4 | |
| SCHEMBL31055029 | 0.72 | POLB (0.56) | SMN1; SMN2MAPTALDH1A1ALPIALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143454-A1 | Pyrazoline Derivatives and Their Use As Pesticides | BAYER CROPSCIENCE AG (DE) | 2009-06-04 | — | — | US | disclosed |
| US-20090143454-A1 | Pyrazoline Derivatives and Their Use As Pesticides | BAYER CROPSCIENCE AG (DE) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143454-A1 | Pyrazoline Derivatives and Their Use As Pesticides | DDT, CHRM1, CHRM2 | SMN1; SMN2 3600/4885MAPT 4108/4885ALDH1A1 990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.