Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5187476 | 0.72 | CA12 (0.57) | CA1CA2CA12CA7CA14 | |
| SCHEMBL1806454 | 0.72 | GFER (0.59) | ALDH1A1HSD17B10CA1CA2CA12 | |
| SCHEMBL2183851 | 0.72 | ALDH1A1 (0.38) | ALDH1A1HSD17B10CA1CA2CA12 | |
| SCHEMBL25860260 | 0.72 | DRD2 (0.48) | ALDH1A1HSD17B10CA1CA2CA12 | |
| SCHEMBL24474079 | 0.71 | ALDH1A1 (0.48) | ALDH1A1HSD17B10CA1CA2CA12 | |
| Ammonia Solution, Strong SCHEMBL28876276 | 0.71 | ALDH1A1 (0.37) | ALDH1A1HSD17B10CA1CA2CA12 | |
| SCHEMBL29768655 | 0.71 | CASP3 (0.39) | ALDH1A1HSD17B10CA1CA2CA12 | |
| SCHEMBL9236433 | 0.69 | CA12 (0.71) | ALDH1A1HSD17B10CA1CA2CA12 | |
| SCHEMBL20262174 | 0.69 | ALDH1A1 (0.47) | ALDH1A1HSD17B10CA1CA2CA12 | |
| SCHEMBL6442704 | 0.69 | ALDH1A1 (0.36) | ALDH1A1HSD17B10CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107257791-A | It is used as the benzimidazole sulfonamides derivative of the orphan receptor γ ROR γ (t) related to biostearin inverse agonist | 盖尔德马研究及发展公司 | 2017-10-17 | — | — | CN | disclosed |
| US-20090069341-A1 | INHIBITORS OF HSP90 | CHENE PATRICK | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069341-A1 | INHIBITORS OF HSP90 | HSP90AB1, HSP90B1, HSP90AA1 | ALDH1A1 2811/4885HSD17B10 1119/4885CA1 4849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.