Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.48 |
| ▸ | F13A1 | P00488 | 4/20 | 0.46 |
| ▸ | TGM1 | P22735 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4145495 | 0.88 | F13A1 (0.44) | NPY5RF13A1TGM1MEN1KMT2A | |
| SCHEMBL4127774 | 0.86 | KMT2A (0.45) | MEN1KMT2AALDH1A1HTTSLC10A6 | |
| SCHEMBL4140333 | 0.83 | HTT (0.40) | NPY5RF13A1TGM1MEN1KMT2A | |
| SCHEMBL4140336 | 0.83 | HTT (0.40) | NPY5RF13A1TGM1MEN1KMT2A | |
| SCHEMBL4134999 | 0.77 | GSTO1 (0.44) | MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7898704 | 0.77 | NPY5R (0.50) | NPY5RF13A1TGM1MEN1KMT2A | |
| SCHEMBL4148569 | 0.76 | GSTO1 (0.43) | ALDH1A1L3MBTL1 | |
| SCHEMBL2747531 | 0.76 | KMT2A (0.64) | NPY5RMEN1KMT2AALDH1A1HTT | |
| SCHEMBL7891048 | 0.75 | NPY5R (0.54) | NPY5RF13A1TGM1MEN1KMT2A | |
| SCHEMBL31284709 | 0.74 | KMT2A (0.68) | NPY5RF13A1TGM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105259-A1 | Acyclic 1,4-Diamines and Uses Thereof | SMITHKLINE BEECHAM CORPORATION | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105259-A1 | Acyclic 1,4-Diamines and Uses Thereof | TRPV4, TRPC4, TRPV1 | NPY5R 298/4885F13A1 4183/4885TGM1 2807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.