SCHEMBL414579

SCHEMBL414579

CCCc1cc(C)ccc1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.50
ALOX15 P16050 2/20 0.50
CYP3A4 P08684 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
TP53 P04637 1/20 0.50
THRB P10828 1/20 0.50
TAAR1 Q96RJ0 1/20 0.45
ALDH1A1 P00352 3/20 0.43
SKP2 Q13309 1/20 0.41
HSD17B10 Q99714 1/20 0.40
CA1 P00915 1/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
TSHR P16473 1/20 0.38
NOS3 P29474 1/20 0.38
NOS1 P29475 1/20 0.38
NOS2 P35228 1/20 0.38
SLC6A4 P31645 2/20 0.37
SLC6A3 Q01959 2/20 0.37
SLC6A2 P23975 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL3634662 0.98 TDP1 (0.48) TDP1ALOX15CYP3A4SMN1; SMN2TP53
SCHEMBL4455067 0.88 SKP2 (0.52) TDP1ALOX15CYP3A4SMN1; SMN2TP53
SCHEMBL4410768 0.83 TDP1 (0.50) TDP1ALOX15CYP3A4SMN1; SMN2TP53
SCHEMBL2014732 0.83 TAAR1 (0.67) TDP1ALOX15CYP3A4SMN1; SMN2TP53
SCHEMBL3682215 0.82 TDP1 (0.54) TDP1ALOX15CYP3A4SMN1; SMN2TP53
SCHEMBL1173554 0.81 ALOX15 (0.48) TDP1ALOX15CYP3A4SMN1; SMN2TP53
SCHEMBL7398269 0.81 TDP1 (0.48) TDP1ALOX15CYP3A4SMN1; SMN2TP53
SCHEMBL5380955 0.80 ALDH1A1 (0.45) TDP1ALOX15CYP3A4SMN1; SMN2TP53
SCHEMBL30087007 0.80 PRKCI (0.42) TDP1ALOX15CYP3A4TP53THRB
SCHEMBL146162 0.80 PRKCI (0.42) TDP1ALOX15CYP3A4TP53THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12543674-B2 Embryogenesis factors for cellular reprogramming of a plant cell PIONEER HI-BRED INTERNATIONAL, INC. (US) 2026-02-10 US disclosed
US-20250277230-A1 PARTHENOGENESIS METHODS AND COMPOSITIONS PIONEER HI-BRED INTERNATONAL, INC. (US) 2025-09-04 US disclosed
US-20250115927-A1 METHODS FOR CLONAL PLANT PRODUCTION PIONEER HI-BRED INTERNATIONAL, INC. (US) 2025-04-10 US disclosed
US-20250115924-A1 SYSTEMS AND METHODS FOR CELLULAR REPROGRAMMING OF A PLANT CELL PIONEER HI-BRED INTERNATIONAL, INC. (US) 2025-04-10 US disclosed
US-20250101453-A1 METHODS OF PARTHENOGENIC HAPLOID INDUCTION AND HAPLOID CHROMOSOME DOUBLING PIONEER HI-BRED INTERNATIONAL, INC. (US) 2025-03-27 US disclosed
US-12146147-B2 Methods for clonal plant production PIONEER HI-BRED INTERNATIONAL, INC. (US) 2024-11-19 US disclosed
US-20240002877-A1 PARTHENOGENESIS FACTORS AND METHODS OF USING SAME PIONEER HI-BRED INTERNATIONAL, INC. (US) 2024-01-04 US disclosed
US-20230407324-A1 DOUBLED HAPLOID INDUCER PIONEER HI-BRED INTERNATIONAL, INC. (US) 2023-12-21 US disclosed
US-20230203516-A1 SYSTEMS AND METHODS FOR CELLULAR REPROGRAMMING OF A PLANT CELL PIONEER HI-BRED INTERNATIONAL, INC. (US) 2023-06-29 US disclosed
US-20230189734-A1 EMBRYOGENESIS FACTORS FOR CELLULAR REPROGRAMMING OF A PLANT CELL PIONEER HI-BRED INTERNATIONAL, INC. (US) 2023-06-22 US disclosed
US-20130205438-A1 DOUBLING OF CHROMOSOMES IN HAPLOID EMBRYOS PIONEER HI BRED INTERNATIONAL INC (US) 2013-08-08 US disclosed
US-20120311736-A1 SELECTIVE ABLATION OF DIPLOID EMBRYOS E.I. du Pont de Nemours and Company and Pioneer Hi-Bred International 2012-12-06 US disclosed
US-8269061-B2 Selective ablation of diploid embryos E.I. du Pont de Nmeours and Company (US) 2012-09-18 US disclosed
US-20120023612-A1 SELECTIVE ABLATION OF DIPLOID EMBRYOS E. I. DU PONT DE NEMOURS AND COMPANY AND PIONEER HI-BRED INTERNATIONAL, INC. (US) 2012-01-26 US disclosed
WO-2011149833-A2 IMPROVED WEED CONTROL AND ROOT BARRIER RUSKIN RODNEY (US) 2011-12-01 WO disclosed
US-20080216191-A1 Pollinating silks of maize ear, contacting haploid embryo with chromosome doubling agent (colchicine), propagate cells; generating homozygosity in plants PIONEER HI-BRED INTERNATIONAL, INC. (US) 2008-09-04 US disclosed
US-20080189801-A1 Selective Ablation of Diploid Embryos PIONNER HI-BRED INTERNATIONAL, INC. 2008-08-07 US disclosed
US-6015845-A Binder for building structure ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2000-01-18 US disclosed
US-4961179-A ACRYLATED COMPOUNDS BLENDED WITH AROMATIC OLEFINS AND DIENES; OPTICAL OR MAGNETIC READABLE OR WRITABLE BAYER AKTIENGESELLSCHAFT (DE) 1990-10-02 US disclosed
US-4908216-A Apparatus for the production of low tension moulded parts BAYER AKTIENGESELLSCHAFT (DE) 1990-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12543674-B2 Embryogenesis factors for cellular reprogramming of a plant cell CCNB2, CCNB1, CCNB3 TDP1 3165/4885ALOX15 3110/4885CYP3A4 4593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.