Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517841 | 0.92 | TDP1 (0.42) | ALDH1A1HSD17B10KMT2AMAPTMEN1 | |
| SCHEMBL25885669 | 0.89 | ALDH1A1 (0.38) | ALDH1A1HSD17B10KMT2AMAPTMEN1 | |
| SCHEMBL5377476 | 0.87 | SKP2 (0.48) | ALDH1A1HSD17B10KMT2AMAPTMEN1 | |
| SCHEMBL10424535 | 0.85 | TLR8 (0.44) | ALDH1A1HSD17B10KMT2AMAPTMEN1 | |
| SCHEMBL30087007 | 0.82 | PRKCI (0.42) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL146162 | 0.82 | PRKCI (0.42) | ALDH1A1KMT2AMAPTMEN1MAPK1 | |
| SCHEMBL29404321 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HSD17B10KMT2AMAPTMEN1 | |
| SCHEMBL137005 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HSD17B10KMT2AMAPTMEN1 | |
| SCHEMBL8076064 | 0.81 | SKP2 (0.43) | ALDH1A1HSD17B10KMT2AMAPTMEN1 | |
| SCHEMBL414579 | 0.80 | TDP1 (0.50) | ALDH1A1HSD17B10MAPTMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105860571-B | A kind of preparation method of Indian yellow N R | 海宁德尔化工有限公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-105860571-A | Preparation method of acid yellow N-R | 海宁德尔化工有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-105802274-A | Preparation method of acid orange O-R | 海宁德尔化工有限公司 | 2016-07-27 | — | — | CN | disclosed |
| US-7202359-B2 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2007-04-10 | — | — | US | disclosed |
| US-20050085634-A1 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2005-04-21 | — | — | US | disclosed |
| US-20040068084-A1 | Azaoxa heterocyclic compound and method of preparing the same | CHANG CHUN PLASTICS CO., LTD. (TW) | 2004-04-08 | — | — | US | disclosed |
| US-5493011-A | PIGMENTING HIGH MOLECULAR WEIGHT NATURAL OR SYNTHETIC ORGANIC MATERIALS | HOECHST AG (DE) | 1996-02-20 | — | — | US | disclosed |
| EP-0518909-B1 | WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE | HOECHST AG (DE) | 1994-05-25 | — | — | EP | disclosed |
| EP-0518909-A1 | WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE. | HOECHST AG (DE) | 1992-12-23 | — | — | EP | disclosed |
| WO-1991013941-A1 | WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068084-A1 | Azaoxa heterocyclic compound and method of preparing the same | AOX1, KDM1A, BMI1 | ALDH1A1 81/4885HSD17B10 2457/4885KMT2A 23/4885 |
| US-20050085634-A1 | Azaoxa heterocyclic compound and method of preparing the same | AOX1, KDM1A, BMI1 | ALDH1A1 116/4885HSD17B10 2547/4885KMT2A 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.