Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13850446 | 0.91 | CCR5 (0.49) | CCR5KDM4EALDH1A1LMNAGAA | |
| SCHEMBL4136272 | 0.83 | MEN1 (0.48) | CCR5KDM4EKMT2A | |
| SCHEMBL30696783 | 0.80 | EPHX2 (0.56) | KDM4EALDH1A1LMNAGAAHTT | |
| SCHEMBL4145891 | 0.78 | LTA4H (0.56) | KDM4EALDH1A1SMN1; SMN2LTA4H | |
| SCHEMBL803672 | 0.76 | SIGMAR1 (0.59) | OPRM1 | |
| SCHEMBL30696817 | 0.75 | EPHX2 (0.56) | KDM4EALDH1A1KMT2AMAOBFAAH | |
| SCHEMBL26985807 | 0.75 | KDM4E (0.55) | KDM4EALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL30696767 | 0.75 | EPHX2 (0.58) | KDM4EMAOBFAAHHRH1 | |
| SCHEMBL31755688 | 0.74 | BCHE (0.43) | KDM4EALDH1A1LMNAGAAHTT | |
| SCHEMBL31506023 | 0.74 | BCHE (0.43) | KDM4EALDH1A1LMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1939202-A1 | NOVEL ADENINE COMPOUND | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2008-07-02 | — | — | EP | disclosed |