Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8424856 | 0.94 | MEN1 (0.63) | MEN1KMT2AMAPTLMNAHPGD | |
| SCHEMBL5909057 | 0.89 | CA12 (0.58) | MEN1KMT2AMAPTLMNAHPGD | |
| Trifluoroacetic Acid SCHEMBL30664874 | 0.88 | MEN1 (0.57) | MEN1KMT2AMAPTLMNAHPGD | |
| Chlorobenzene SCHEMBL27766061 | 0.84 | NPC1 (0.55) | MEN1KMT2AMAPTLMNAHPGD | |
| SCHEMBL6359975 | 0.84 | CYP1A2 (0.68) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL8235829 | 0.83 | ALDH1A1 (0.66) | MEN1KMT2AMAPTLMNAHPGD | |
| SCHEMBL10873630 | 0.83 | CYP1A2 (0.62) | MEN1KMT2AMAPTLMNAHPGD | |
| Chlorobenzene SCHEMBL28001559 | 0.83 | LMNA (0.52) | MEN1KMT2AMAPTLMNAHPGD | |
| Chlorobenzene SCHEMBL27766117 | 0.83 | SLC6A9 (0.55) | MEN1KMT2AMAPTLMNAHPGD | |
| Morpholine SCHEMBL28644462 | 0.83 | LMNA (0.52) | MEN1KMT2AMAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751123-B1 | Method for producing alkylsulfinylbenzamides | SUMITOMO SEIKA CHEMICALS (JP) | 2000-05-10 | — | — | EP | claimed |
| US-5672751-A | TREATMENT OF A HALOBENZAMIDE WITH AN ALKANETHIOL IN THE PRESENCE OF A PHASE TRANSFER CATALYST | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-09-30 | — | — | US | claimed |
| EP-0751123-A2 | Method for producing alkylsulfinylbenzamides | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1997-01-02 | — | — | EP | claimed |
| EP-0657438-A2 | Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1995-06-14 | — | — | EP | claimed |
| US-12152049-B2 | STING agonistic compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2024-11-26 | — | — | US | disclosed |
| US-20230339992-A1 | STING AGONISTIC COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2023-10-26 | — | — | US | disclosed |
| EP-4120837-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 2-(3-PHENYLUREIDO)BENZAMIDE, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |
| WO-2021032648-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF LIVER DISEASE | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIV. TRINITY OF QUEEN (IE) | 2021-02-25 | — | — | WO | disclosed |
| US-10654845-B2 | 2-(het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-05-19 | — | — | US | disclosed |
| US-10022354-B2 | Pyrrolidine amide compounds as histone demethylase inhibitors | GENENTECH, INC. (US) | 2018-07-17 | — | — | US | disclosed |
| US-20180016273-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-18 | — | — | US | disclosed |
| US-20170312252-A1 | PYRROLIDINE AMIDE COMPOUNDS AS HISTONE DEMETHYLASE INHIBITORS | WUXI APPTEC (SHANGHAI) CO. LTD (CN) | 2017-11-02 | — | — | US | disclosed |
| US-4151351-A | PROSTAGLANDINS, ANTIINFLAMMATORY | THE UPJOHN COMPANY (US) | 1979-04-24 | — | — | US | disclosed |
| US-4131738-A | 6-Hydroxy-PGE1 compounds | THE UPJOHN COMPANY (US) | 1978-12-26 | — | — | US | disclosed |
| US-4128713-A | 6,7-Didehydro-PGI1 compounds | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |
| US-4126744-A | PROSTACYCLIN, MUSCLE STIMULANTS, PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
| US-4112224-A | PROSTAGLANDIN | THE UPJOHN COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4109082-A | PROSTACYCLIN ANALOGS; SMOOTH MUSCLE STIMULATORS | THE UPJOHN COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4100192-A | Inter-phenylene-PG amides | THE UPJOHN COMPANY (US) | 1978-07-11 | — | — | US | disclosed |
| US-4097489-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180016273-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | CYP4B1, CYP1B1, CYP8B1 | MEN1 2151/4885KMT2A 1263/4885MAPT 4794/4885 |
| US-10654845-B2 | 2-(het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides | CYP4B1, CYP1B1, CYP8B1 | MEN1 2209/4885KMT2A 1302/4885MAPT 4797/4885 |
| US-20170312252-A1 | PYRROLIDINE AMIDE COMPOUNDS AS HISTONE DEMETHYLASE INHIBITORS | KDM5A, KDM5C, KDM5B | MEN1 3356/4885KMT2A 34/4885MAPT 2124/4885 |
| US-10022354-B2 | Pyrrolidine amide compounds as histone demethylase inhibitors | KDM5A, KDM5C, KDM1B | MEN1 3483/4885KMT2A 35/4885MAPT 2084/4885 |
| US-12152049-B2 | STING agonistic compound | STING1, IRF3, MAVS | MEN1 295/4885KMT2A 2971/4885MAPT 4099/4885 |
| US-20230339992-A1 | STING AGONISTIC COMPOUND | STING1, IRF3, MAVS | MEN1 295/4885KMT2A 2971/4885MAPT 4099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.