SCHEMBL4146947

SCHEMBL4146947

Cn1cc(N)c(=O)n(C)c1=S

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 1/20 0.41
AURKA O14965 1/20 0.33
TTK P33981 1/20 0.33
AURKB Q96GD4 1/20 0.33
INCENP Q9NQS7 1/20 0.33
LPO P22079 1/20 0.33
KDM4E B2RXH2 2/20 0.33
KDM4A O75164 1/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
KDM4C Q9H3R0 1/20 0.33
ATAD2 Q6PL18 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL480683 0.77 LMNA (0.39) AURKATTKAURKBINCENPKDM4E
Hydrochloric Acid SCHEMBL30740061 0.76 LMNA (0.38) AURKATTKAURKBINCENPKDM4E
SCHEMBL4152333 0.72 TDP1 (0.41) KDM4EALDH1A1POLBMAPT
SCHEMBL9725941 0.72
SCHEMBL5404635 0.67 TRIM24 (0.40) LPOALDH1A1
SCHEMBL21026204 0.65 AURKA (0.33) AURKATTKAURKBINCENPATAD2
SCHEMBL28313542 0.64 KMT2A (0.35) AURKATTKAURKBINCENPLPO
SCHEMBL9747188 0.64 CASP6 (0.59) CASP6KDM4EKDM4AALDH1A1POLB
SCHEMBL13943567 0.62
SCHEMBL28207015 0.61 ALDH1A1 (0.42) CASP6ALDH1A1ATAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090048374-A1 STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE BAERLOCHER GMBH (DE) 2009-02-19 US disclosed
EP-1996649-A1 STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE Baerlocher GmbH (DE) 2008-12-03 EP disclosed
WO-2007104379-A1 STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS WITH IMPROVED INITIAL COLOR AND IMPROVED COLOR MAINTENANCE BAERLOCHER GMBH (DE) 2007-09-20 WO disclosed