Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 12/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 12/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4148108 | 0.71 | FYN (0.41) | MKNK1MKNK2CCNT1FYNHTT | |
| SCHEMBL4152322 | 0.69 | MKNK1 (0.43) | MKNK1MKNK2CCNT1FYNCYP1A2 | |
| SCHEMBL4148649 | 0.68 | PTGDR (0.39) | MKNK1MKNK2CCNT1FYNCYP1A2 | |
| SCHEMBL4139867 | 0.68 | TPH1 (0.45) | MKNK1MKNK2CCNT1HTTKCNH3 | |
| SCHEMBL4139796 | 0.66 | CYP1A2 (0.47) | MKNK1MKNK2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4139805 | 0.66 | FYN (0.56) | FYNCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4147501 | 0.66 | CCNT1 (0.46) | MKNK1MKNK2CCNT1FYNPTGDR | |
| SCHEMBL4160480 | 0.66 | PDGFRB (0.50) | MKNK1MKNK2CCNT1HTTSMN1; SMN2 | |
| SCHEMBL4161155 | 0.65 | PTGDR (0.51) | MKNK1MKNK2CCNT1HTTKCNH3 | |
| SCHEMBL4142715 | 0.65 | MKNK1 (0.48) | MKNK1MKNK2CCNT1FYNSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163515-A1 | Compounds Which Bind to the Active Site of Protein Kinase Enzymes | BIOFOCUS DISCOVERY LTD. | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163515-A1 | Compounds Which Bind to the Active Site of Protein Kinase Enzymes | ROCK1, ROCK2, CIT | MKNK1 210/4885MKNK2 213/4885CCNT1 3712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.