SCHEMBL6302452

SCHEMBL6302452

O=C(C=CC(=O)Nc1ccccc1)Nc1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 4/20 0.73
MMP2 P08253 4/20 0.73
MMP9 P14780 4/20 0.73
MAOB P27338 3/20 0.73
EGFR P00533 1/20 0.73
MAOA P21397 1/20 0.73
TGM2 P21980 1/20 0.68
MAPT P10636 5/20 0.68
ALDH1A1 P00352 4/20 0.68
KDM4E B2RXH2 1/20 0.68
LPAR2 Q9HBW0 2/20 0.67
LPAR1 Q92633 1/20 0.67
MEN1 O00255 1/20 0.63
KMT2A Q03164 1/20 0.63
LPAR3 Q9UBY5 2/20 0.63
CYP1A2 P05177 1/20 0.63
NPSR1 Q6W5P4 1/20 0.63
NPC1 O15118 1/20 0.61
RAB9A P51151 1/20 0.61
TP53 P04637 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9840923 1.00 MMP1 (0.73) MMP1MMP2MMP9MAOBEGFR
SCHEMBL6302448 1.00 MMP1 (0.73) MMP1MMP2MMP9MAOBEGFR
SCHEMBL2831352 0.93 ALDH1A1 (0.79) MMP1MMP2MMP9MAOBEGFR
SCHEMBL1169889 0.93 ALDH1A1 (0.79) MMP1MMP2MMP9MAOBEGFR
SCHEMBL1683255 0.93 ALDH1A1 (0.79) MMP1MMP2MMP9MAOBEGFR
SCHEMBL15667293 0.91 ALDH1A1 (0.76) MMP1MMP2MMP9MAOBEGFR
SCHEMBL11502177 0.91 CASP3 (0.67) MMP1MMP2MMP9MAOBEGFR
SCHEMBL29262225 0.91 ALDH1A1 (0.76) MMP1MMP2MMP9MAOBEGFR
SCHEMBL9360711 0.91 ALDH1A1 (0.76) MMP1MMP2MMP9MAOBEGFR
SCHEMBL6295972 0.91 MAOB (0.79) MMP1MMP2MMP9MAOBEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6863719-B2 Ink jet ink with improved reliability LEXMARK INTERNATIONAL, INC. (US) 2005-03-08 US disclosed
US-20040123773-A1 Ink jet ink with improved reliability FUNAI ELECTRIC CO., LTD (JP) 2004-07-01 US disclosed
US-6254669-B1 Bleed reduction agents for ink printing inks ZENECA LIMITED (GB) 2001-07-03 US disclosed
EP-0471454-B1 Reactive pyridone azo dyestuffs ZENECA LTD (GB) 1996-12-04 EP disclosed
EP-0468649-B1 Anionic compounds ZENECA LTD (GB) 1996-05-15 EP disclosed
EP-0468647-B1 Anionic compounds ZENECA LTD (GB) 1996-03-13 EP disclosed
EP-0468648-B1 Anionic bis(hydroxynaphthylamino) disazo dyestuffs and use thereof for ink jet printing ZENECA LTD (GB) 1995-09-20 EP disclosed
US-5262527-A Disazo dyes suitable for use in ink jet printing IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-11-16 US disclosed
US-4530952-A Blend containing diamide compound MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1985-07-23 US disclosed
US-4156065-A 1-OXIDE, 1-SULFIDE, OR 1-HYDROCARBYLIMINO DERIVATIVE OF A PHOSPHOLENE, PHOSPHOLANE, OR PHOSPHETANE THE UPJOHN COMPANY (US) 1979-05-22 US disclosed