SCHEMBL9840923

SCHEMBL9840923

O=C(/C=C\C(=O)Nc1ccccc1)Nc1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 4/20 0.73
MMP2 P08253 4/20 0.73
MMP9 P14780 4/20 0.73
MAOB P27338 3/20 0.73
EGFR P00533 1/20 0.73
MAOA P21397 1/20 0.73
TGM2 P21980 1/20 0.68
MAPT P10636 5/20 0.68
ALDH1A1 P00352 4/20 0.68
KDM4E B2RXH2 1/20 0.68
LPAR2 Q9HBW0 2/20 0.67
LPAR1 Q92633 1/20 0.67
MEN1 O00255 1/20 0.63
KMT2A Q03164 1/20 0.63
LPAR3 Q9UBY5 2/20 0.63
CYP1A2 P05177 1/20 0.63
NPSR1 Q6W5P4 1/20 0.63
NPC1 O15118 1/20 0.61
RAB9A P51151 1/20 0.61
TP53 P04637 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6302448 1.00 MMP1 (0.73) MMP1MMP2MMP9MAOBEGFR
SCHEMBL6302452 1.00 MMP1 (0.73) MMP1MMP2MMP9MAOBEGFR
SCHEMBL2831352 0.93 ALDH1A1 (0.79) MMP1MMP2MMP9MAOBEGFR
SCHEMBL1169889 0.93 ALDH1A1 (0.79) MMP1MMP2MMP9MAOBEGFR
SCHEMBL1683255 0.93 ALDH1A1 (0.79) MMP1MMP2MMP9MAOBEGFR
SCHEMBL15667293 0.91 ALDH1A1 (0.76) MMP1MMP2MMP9MAOBEGFR
SCHEMBL11502177 0.91 CASP3 (0.67) MMP1MMP2MMP9MAOBEGFR
SCHEMBL29262225 0.91 ALDH1A1 (0.76) MMP1MMP2MMP9MAOBEGFR
SCHEMBL9360711 0.91 ALDH1A1 (0.76) MMP1MMP2MMP9MAOBEGFR
SCHEMBL6295972 0.91 MAOB (0.79) MMP1MMP2MMP9MAOBEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12371447-B2 Method for producing (meth)acryloxy group-containing organosilicon compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-07-29 US disclosed
US-20230134471-A1 METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-04 US disclosed
US-4990428-A Photopolymerizable compound overcoating aluminum(or alloy therof), and aluminum oxide layers MITSUBISHI KASEI CORPORATION (JP) 1991-02-05 US disclosed
EP-0179448-B1 PHOTOSENSITIVE PLANOGRAPHIC PRINTING PLATE MITSUBISHI KASEI CORPORATION (JP) 1990-04-18 EP disclosed
EP-0179448-A2 Photosensitive planographic printing plate MITSUBISHI KASEI CORPORATION (JP) 1986-04-30 EP disclosed
US-4156065-A 1-OXIDE, 1-SULFIDE, OR 1-HYDROCARBYLIMINO DERIVATIVE OF A PHOSPHOLENE, PHOSPHOLANE, OR PHOSPHETANE THE UPJOHN COMPANY (US) 1979-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12371447-B2 Method for producing (meth)acryloxy group-containing organosilicon compounds HM13, RPS13, GRHPR MMP1 2736/4885MMP2 3924/4885MMP9 2695/4885
US-20230134471-A1 METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS HM13, RPS13, GRHPR MMP1 2736/4885MMP2 3924/4885MMP9 2695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.