Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 2/20 | 0.42 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29099329 | 0.98 | NAMPT (0.45) | NAMPTCYP2C9CYP2C19HDAC4HDAC6 | |
| SCHEMBL28317573 | 0.86 | ALDH1A1 (0.44) | NAMPTTSHRACACBALDH1A1KMT2A | |
| SCHEMBL29804262 | 0.85 | HDAC4 (0.43) | NAMPTCYP2C9CYP2C19HDAC4HDAC6 | |
| SCHEMBL3139874 | 0.79 | ALDH1A1 (0.35) | NAMPTTSHRACACBMEN1ALDH1A1 | |
| SCHEMBL15419308 | 0.77 | NPC1 (0.46) | CYP1A2TSHRACACBALDH1A1CA12 | |
| Hydrochloric Acid SCHEMBL28665424 | 0.77 | CHRNA4 (0.41) | CYP2C19CYP1A2TSHRACACBMEN1 | |
| SCHEMBL15465637 | 0.77 | HDAC4 (0.40) | NAMPTCYP2C9CYP2C19HDAC4HDAC6 | |
| SCHEMBL3827774 | 0.75 | TBXAS1 (0.43) | CYP2C19CYP1A2TSHRALDH1A1ADORA3 | |
| SCHEMBL23042189 | 0.74 | CHRNA4 (0.36) | CYP2C9CYP2C19ACACBALDH1A1CA12 | |
| SCHEMBL8551555 | 0.74 | CYP1A2 (0.47) | NAMPTCYP2C19CYP1A2ACACBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 362 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120058630-A | Triaryl substituted vinyl compound and synthesis method thereof | 海南大学 | 2025-05-30 | — | — | CN | claimed |
| CN-120040371-A | Compound capable of degrading MYC in targeted manner and application thereof | 中国医学科学院医药生物技术研究所 | 2025-05-27 | — | — | CN | claimed |
| US-11535833-B2 | Carboxyesterase biocatalysts | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2022-12-27 | — | — | US | claimed |
| CN-108863971-B | 2- (2, 4, 6-trimethylphenylseleno) -1, 3-oxazole-5 ethyl carboxylate compound and preparation method thereof | 温州医科大学 | 2021-06-15 | — | — | CN | claimed |
| US-20210115417-A1 | CARBOXYESTERASE BIOCATALYSTS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2021-04-22 | — | — | US | claimed |
| EP-3724324-A1 | CARBOXYESTERASE BIOCATALYSTS | GlaxoSmithKline Intellectual Property Development Ltd (GB) | 2020-10-21 | — | — | EP | claimed |
| CN-111465688-A | Carboxylic acid ester enzyme catalysts | 葛兰素史密斯克莱知识产权发展有限公司 | 2020-07-28 | — | — | CN | claimed |
| CN-106632134-B | 2- (4-thiazolinone-2-imino) thiazole-5-carboxylic ester and preparation method and application thereof | 湖南大学 | 2020-01-03 | — | — | CN | claimed |
| CN-110114358-A | Novel compound and pharmacologically acceptable salt thereof | 明治制果药业株式会社 | 2019-08-09 | — | — | CN | claimed |
| WO-2019116311-A1 | CARBOXYESTERASE BIOCATALYSTS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-06-20 | — | — | WO | claimed |
| CN-116507617-B | 1- (2- (4-Cyclopropyl-1H-1, 2, 3-triazol-1-yl) acetyl) -4-hydroxypyrrolidine-2-carboxamide derivatives as VHL inhibitors | 基因泰克公司 | 2026-05-22 | — | — | CN | disclosed |
| CN-122070275-A | Heterocyclic compound and application thereof | 成都麻沸散医药科技有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-122011039-A | Large-steric-hindrance triazole carbene monodentate palladium compound containing surplus N, N chelating ligand, and preparation method and application thereof | 江苏科技大学 | 2026-05-12 | — | — | CN | disclosed |
| EP-3985001-B1 | PHARMACEUTICAL COMPOSITION FOR USE IN TREATING A CANCER | SERVIER LAB (FR) | 2026-04-29 | — | — | EP | disclosed |
| EP-4727546-A2 | PROTEOSOME COMPLEX INHIBITORS TARGETING CLPP1P2 PROTEASE | The Global Alliance for TB Drug Development, Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| US-20120021074-A1 | P2X3, RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN | MERCK SHARP & DOHME CORP. (US) | 2012-01-26 | — | — | US | disclosed |
| WO-2010142934-A1 | INDOLE DERIVATIVES AS LIGANDS OF CRTH2 RECEPTORS | PULMAGEN THERAPEUTICS (ASTHMA) LIMITED (GB) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010142801-A1 | INDOLE AMIDE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010111059-A1 | P2X3 RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN | MERCK SHARP & DOHME CORP. (US) | 2010-09-30 | — | — | WO | disclosed |
| WO-2010111059-A1 | P2X3 RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN | MERCK SHARP & DOHME CORP. (US) | 2010-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021074-A1 | P2X3, RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN | P2RX3, P2RX1, P2RX2 | NAMPT 1896/4885CYP2C9 3902/4885CYP2C19 3558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.