Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.45 |
| ▸ | BRS3 | P32247 | 5/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3297131 | 0.81 | PRKAB2 (0.55) | ALDH1A1PTPN11FFAR4BRS3KCNH2 | |
| SCHEMBL28247966 | 0.80 | LTB4R2 (0.48) | ALDH1A1PTPN11FFAR4BRS3FNTA | |
| SCHEMBL4988323 | 0.79 | NPC1 (0.59) | ALDH1A1PTPN11FFAR4LTB4R2 | |
| SCHEMBL9723854 | 0.79 | PTPN11 (0.74) | ALDH1A1PTPN11 | |
| SCHEMBL10800801 | 0.79 | PTPN11 (0.74) | ALDH1A1PTPN11 | |
| SCHEMBL17835424 | 0.79 | PTPN11 (0.74) | ALDH1A1PTPN11 | |
| SCHEMBL6265322 | 0.79 | PTPN11 (0.74) | ALDH1A1PTPN11 | |
| SCHEMBL10397754 | 0.79 | PTPN11 (0.74) | ALDH1A1PTPN11 | |
| SCHEMBL9407174 | 0.79 | PTPN11 (0.74) | ALDH1A1PTPN11 | |
| SCHEMBL6913917 | 0.79 | PTPN11 (0.70) | ALDH1A1PTPN11LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090030218-A1 | Method For Producing Aminoalcohol Derivative Having Biphenyl Group | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-01-29 | — | — | US | claimed |
| EP-1932826-A1 | METHOD FOR PRODUCING AMINOALCOHOL DERIVATIVE HAVING BIPHENYL GROUP | Kissei Pharmaceutical Co., Ltd. (JP) | 2008-06-18 | — | — | EP | claimed |
| US-20090030218-A1 | Method For Producing Aminoalcohol Derivative Having Biphenyl Group | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-01-29 | — | — | US | disclosed |
| EP-1932826-A1 | METHOD FOR PRODUCING AMINOALCOHOL DERIVATIVE HAVING BIPHENYL GROUP | Kissei Pharmaceutical Co., Ltd. (JP) | 2008-06-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030218-A1 | Method For Producing Aminoalcohol Derivative Having Biphenyl Group | ALDH7A1, DDC, ADH5 | ALDH1A1 16/4885PTPN11 3466/4885FFAR4 731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.