Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 16/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4167024 | 0.89 | TRPV1 (0.54) | TRPV1EGFR | |
| SCHEMBL5470970 | 0.81 | TRPV1 (0.53) | TRPV1 | |
| SCHEMBL4155409 | 0.78 | KDM4E (0.48) | TRPV1EGFR | |
| SCHEMBL5474291 | 0.77 | SLC2A1 (0.56) | TRPV1SLC2A1 | |
| SCHEMBL4150099 | 0.76 | TRPV1 (0.56) | TRPV1 | |
| SCHEMBL4158353 | 0.76 | TRPV1 (0.44) | TRPV1 | |
| SCHEMBL5486026 | 0.75 | MAPT (0.57) | TRPV1 | |
| SCHEMBL4154147 | 0.75 | TRPV1 (0.47) | TRPV1EGFR | |
| SCHEMBL4146059 | 0.75 | HCAR1 (0.45) | SLC2A1 | |
| SCHEMBL13801568 | 0.74 | TRPV1 (0.60) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156598-A1 | Imidazolopyrimidine modulators of TRPV1 | JANSSEN PHARMACEUTICA NV (BE) | 2009-06-18 | — | — | US | claimed |
| US-20090156598-A1 | Imidazolopyrimidine modulators of TRPV1 | JANSSEN PHARMACEUTICA NV (BE) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156598-A1 | Imidazolopyrimidine modulators of TRPV1 | TRPV1, TRPV2, TRPV5 | TRPV1 1/4885SLC2A1 3849/4885EGFR 2826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.