Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | PDE9A | O76083 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4151365 | 0.72 | HTR2A (0.48) | HTR2AHTR2CKCNH2ALDH1A1KDM4E | |
| SCHEMBL3164357 | 0.66 | HTR2A (0.70) | HTR2AHTR2CKCNH2PTGS2MEN1 | |
| Pyridine SCHEMBL28512865 | 0.66 | BRAF (0.44) | HTR2APTGS2HTR6ALDH1A1KDM4E | |
| SCHEMBL3164364 | 0.66 | HTR2A (0.70) | HTR2AHTR2CKCNH2PTGS2MEN1 | |
| SCHEMBL3390895 | 0.66 | HTR2A (0.51) | HTR2AHTR2CKCNH2HTR6ALDH1A1 | |
| SCHEMBL28028239 | 0.65 | FASN (0.45) | CXCR2ALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL1993674 | 0.65 | HTR2A (0.50) | HTR2AHTR2CKCNH2HTR6ALDH1A1 | |
| SCHEMBL4069294 | 0.65 | ABL1 (0.45) | HTR2AHTR2CKCNH2PTGS2MEN1 | |
| SCHEMBL15330358 | 0.64 | PIM1 (0.45) | PTGS2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL11686034 | 0.64 | HTR6 (0.44) | PTGS2HTR6CA1CA2FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012134-A1 | Arylsulfonyl Benzofused Heterocycles as 5-Ht2a Antagonists | CURTIS NEIL ROY | 2009-01-08 | — | — | US | claimed |
| US-20090012134-A1 | Arylsulfonyl Benzofused Heterocycles as 5-Ht2a Antagonists | CURTIS NEIL ROY | 2009-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012134-A1 | Arylsulfonyl Benzofused Heterocycles as 5-Ht2a Antagonists | HTR2A, HTR2C, HTR2B | HTR2A 1/4885HTR2C 2/4885KCNH2 544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.