Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4151018 | 1.00 | CNR2 (0.40) | CNR2PIN1FBP1TSHRABCB11 | |
| SCHEMBL4362447 | 0.81 | CYP3A4 (0.36) | TSHRCYP3A4POLBNPSR1MAPT | |
| SCHEMBL5967286 | 0.81 | MAPT (0.40) | CNR2PIN1TSHRPOLBNPSR1 | |
| SCHEMBL11844527 | 0.79 | MAPT (0.43) | TSHRCYP1A2NPSR1MAPTKDM4E | |
| SCHEMBL841159 | 0.76 | NPSR1 (0.49) | PIN1TSHRPOLBNPSR1MAPT | |
| SCHEMBL5807773 | 0.75 | PIN1 (0.57) | PIN1TSHRPOLBNPSR1 | |
| SCHEMBL9290105 | 0.75 | CNR2 (0.45) | CNR2PIN1TSHRABCB11CYP1A2 | |
| SCHEMBL13574069 | 0.75 | PIN1 (0.57) | PIN1TSHRPOLBNPSR1 | |
| SCHEMBL8893037 | 0.74 | ESR1 (0.50) | CNR2PIN1TSHRABCB11CYP1A2 | |
| SCHEMBL22938122 | 0.74 | CES2 (0.39) | MAPTMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090311318-A1 | SUBSTITUTED (S)-BENZOXAZINONES | P&H THERAPEUTICS, INC. (US) | 2009-12-17 | — | — | US | disclosed |
| US-20090311318-A1 | SUBSTITUTED (S)-BENZOXAZINONES | P&H THERAPEUTICS, INC. (US) | 2009-12-17 | — | — | US | disclosed |
| US-20090311318-A1 | SUBSTITUTED (S)-BENZOXAZINONES | P&H THERAPEUTICS, INC. (US) | 2009-12-17 | — | — | US | disclosed |
| WO-2009108722-A2 | SUBSTITUTED BENZOXAZINONES | P & H THERAPEUTICS, INC. (US) | 2009-09-03 | — | — | WO | disclosed |
| US-20090215763-A1 | SUBSTITUTED BENZOXAZINONES | P&H THERAPEUTICS, INC. (US) | 2009-08-27 | — | — | US | disclosed |
| US-20090215763-A1 | SUBSTITUTED BENZOXAZINONES | P&H THERAPEUTICS, INC. (US) | 2009-08-27 | — | — | US | disclosed |
| US-20090215763-A1 | SUBSTITUTED BENZOXAZINONES | P&H THERAPEUTICS, INC. (US) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215763-A1 | SUBSTITUTED BENZOXAZINONES | REN, ACE, AGTR1 | CNR2 2703/4885PIN1 3116/4885FBP1 633/4885 |
| US-20090311318-A1 | SUBSTITUTED (S)-BENZOXAZINONES | REN, ACE, AGTR1 | CNR2 2464/4885PIN1 2146/4885FBP1 1123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.