Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | LAP3 | P28838 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14066236 | 0.79 | ALDH1A1 (0.61) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL6575848 | 0.79 | ALDH1A1 (0.61) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL366832 | 0.79 | ALDH1A1 (0.61) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL1600361 | 0.79 | ALDH1A1 (0.61) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL4661209 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL27690076 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL8426058 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL6012976 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL7400240 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL8695483 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KMT2ASLC6A2SLC6A3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023860-B2 | Pro-drugs for controlled release of biologically active compounds | SIGNATURE THERAPEUTICS, INC. (US) | 2015-05-05 | — | — | US | disclosed |
| US-20090137618-A1 | PRO-DRUGS FOR CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS | 3I, LP | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137618-A1 | PRO-DRUGS FOR CONTROLLED RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS | CRH, FURIN, PEPD | ALDH1A1 2963/4885KMT2A 4268/4885SLC6A2 140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.