SCHEMBL7400240

SCHEMBL7400240

CNCC(NC)C(=O)OCc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
KMT2A Q03164 2/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A3 Q01959 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
TACR1 P25103 1/20 0.47
LMNA P02545 1/20 0.46
MAPK1 P28482 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
POLB P06746 1/20 0.45
MAPT P10636 2/20 0.44
S1PR1 P21453 2/20 0.44
RAB9A P51151 2/20 0.44
NPC1 O15118 1/20 0.44
HPGD P15428 1/20 0.44
CTSK P43235 3/20 0.44
GAA P10253 1/20 0.43
ACE P12821 1/20 0.43
S1PR4 O95977 1/20 0.43
CTSL P07711 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2059140 0.85 TACR1 (0.58) ALDH1A1TACR1POLBMAPTS1PR1
SCHEMBL8351818 0.85 ALDH1A1 (0.53) ALDH1A1KMT2ASLC6A2SLC6A3TDP1
SCHEMBL21444696 0.85 ALDH1A1 (0.53) ALDH1A1KMT2ASLC6A2SLC6A3TDP1
SCHEMBL13108402 0.85 TACR1 (0.58) ALDH1A1TACR1POLBMAPTS1PR1
SCHEMBL8348342 0.85 ALDH1A1 (0.53) ALDH1A1KMT2ASLC6A2SLC6A3TDP1
SCHEMBL23011779 0.84 ALDH1A1 (0.51) ALDH1A1KMT2ASLC6A2SLC6A3TDP1
SCHEMBL20804457 0.84 PPARA (0.53) ALDH1A1KMT2ASLC6A2SLC6A3TDP1
SCHEMBL5019111 0.84 ALDH1A1 (0.51) ALDH1A1TACR1LMNAMAPK1L3MBTL1
SCHEMBL4954521 0.84 CTRB1 (0.52) ALDH1A1KMT2ASLC6A2SLC6A3TDP1
Hydrochloric Acid SCHEMBL30844650 0.84 ALDH1A1 (0.51) ALDH1A1KMT2ASLC6A2SLC6A3TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0688314-B1 PRODRUG DERIVATIVES OF ENZYME INHIBITORS WITH HYDROXYL GROUPS, METHODS OF PREPARING THEM AND THEIR USE HOECHST AG (DE) 2001-10-04 EP disclosed
US-5804559-A WATER SOLUBILITY HOECHST AKTIENGESELLSCHAFT (DE) 1998-09-08 US disclosed
EP-0688314-A1 PRODRUG DERIVATIVES OF ENZYME INHIBITORS WITH HYDROXYL GROUPS, METHODS OF PREPARING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1995-12-27 EP disclosed
WO-1994021604-A1 PRODRUG DERIVATIVES OF ENZYME INHIBITORS WITH HYDROXYL GROUPS, METHODS OF PREPARING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1994-09-29 WO disclosed
WO-1994013636-A1 NEW SUBSTITUTED AZETIDINONES AS ANTI-INFLAMMATORY AND ANTIDEGENERATIVE AGENTS MERCK & CO., INC. (US) 1994-06-23 WO disclosed