Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.42 |
| ▸ | CES1 | P23141 | 7/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | PPARD | Q03181 | 5/20 | 0.39 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28904768 | 0.87 | THRB (0.35) | — | |
| SCHEMBL28960329 | 0.87 | THRB (0.35) | — | |
| SCHEMBL4152655 | 0.87 | THRB (0.35) | — | |
| SCHEMBL28904773 | 0.85 | THRB (0.32) | — | |
| SCHEMBL10487829 | 0.83 | FAAH (0.43) | FAAHCES1CES2MEN1KMT2A | |
| SCHEMBL4160739 | 0.80 | THRB (0.38) | — | |
| SCHEMBL346289 | 0.80 | THRB (0.38) | — | |
| SCHEMBL870675 | 0.80 | THRB (0.38) | — | |
| SCHEMBL1536996 | 0.80 | THRB (0.38) | — | |
| SCHEMBL5359965 | 0.79 | THRB (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090212467-A1 | Expandable Bladder | PIRELLI PNEUMATICI S.P.A. (IT) | 2009-08-27 | — | — | US | claimed |
| EP-1841576-A1 | EXPANDABLE BLADDER | Pirelli Tyre S.p.A. (IT) | 2007-10-10 | — | — | EP | claimed |
| WO-2006079359-A1 | EXPANDABLE BLADDER | PIRELLI TYRE S.P.A. (IT) | 2006-08-03 | — | — | WO | claimed |
| US-20090212467-A1 | Expandable Bladder | PIRELLI PNEUMATICI S.P.A. (IT) | 2009-08-27 | — | — | US | disclosed |
| EP-1841576-A1 | EXPANDABLE BLADDER | Pirelli Tyre S.p.A. (IT) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006079359-A1 | EXPANDABLE BLADDER | PIRELLI TYRE S.P.A. (IT) | 2006-08-03 | — | — | WO | disclosed |