SCHEMBL4152500

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4139253	0.94	PNMT (0.55)	IDO1TDO2ACP3PNMTALDH1A1
	SCHEMBL14034033	0.86	IDO1 (0.54)	IDO1TDO2ACP3ALDH1A1TSHR
	SCHEMBL11193839	0.82	ALDH1A1 (0.48)	IDO1TDO2ACP3PNMTALDH1A1
	SCHEMBL4154570	0.82	ACP3 (0.55)	IDO1TDO2ACP3ALDH1A1TSHR
	SCHEMBL4601149	0.82	PNMT (0.55)	IDO1TDO2ACP3PNMTALDH1A1
	SCHEMBL13357679	0.80	IDO1 (0.59)	IDO1TDO2ACP3PNMTALDH1A1
	SCHEMBL27946000	0.80	PNMT (0.53)	IDO1TDO2ACP3PNMTALDH1A1
	SCHEMBL22193351	0.78	PNMT (0.61)	IDO1TDO2ACP3PNMTTSHR
	SCHEMBL12971482	0.78	PNMT (0.51)	IDO1TDO2ACP3PNMTALDH1A1
	SCHEMBL7647822	0.78	PNMT (0.51)	IDO1TDO2ACP3PNMTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.