SCHEMBL4601149

SCHEMBL4601149

FC(F)(F)c1cccc(C(Cl)Cl)c1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.55
IDO1 P14902 1/20 0.51
TDO2 P48775 1/20 0.51
ACP3 P15309 2/20 0.50
CES2 O00748 2/20 0.50
TSHR P16473 3/20 0.48
MAPK1 P28482 1/20 0.48
DAO P14920 1/20 0.44
MGLL Q99685 1/20 0.44
OPRM1 P35372 1/20 0.43
OPRD1 P41143 1/20 0.43
OPRK1 P41145 1/20 0.43
OPRL1 P41146 1/20 0.43
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
HTR2B P41595 1/20 0.43
ALDH1A1 P00352 1/20 0.42
KDM1A O60341 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4139253 0.87 PNMT (0.55) PNMTIDO1TDO2ACP3CES2
SCHEMBL27946000 0.85 PNMT (0.53) PNMTIDO1TDO2ACP3CES2
SCHEMBL7647822 0.83 PNMT (0.51) PNMTIDO1TDO2ACP3CES2
SCHEMBL6705910 0.83 PNMT (0.51) PNMTIDO1TDO2ACP3CES2
SCHEMBL8460577 0.83 PNMT (0.51) PNMTIDO1TDO2ACP3CES2
SCHEMBL4069772 0.83 PNMT (0.51) PNMTIDO1TDO2ACP3CES2
SCHEMBL8463699 0.83 PNMT (0.51) PNMTIDO1TDO2ACP3CES2
SCHEMBL12971482 0.83 PNMT (0.51) PNMTIDO1TDO2ACP3CES2
SCHEMBL22193351 0.83 PNMT (0.61) PNMTIDO1TDO2ACP3CES2
SCHEMBL4086256 0.82 PNMT (0.58) PNMTIDO1TDO2ACP3CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3315579-B1 SURFACE TREATMENT AGENT INCLUDING PERFLUORO(POLY)ETHER GROUP-CONTAINING SILANE COMPOUND DAIKIN IND LTD (JP) 2024-05-01 EP claimed
CN-116478066-A Production process of m-trifluoromethyl benzyl cyanide 宁夏思科达生物科技有限公司 2023-07-25 CN claimed
EP-3088487-B1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND DAIKIN IND LTD (JP) 2021-05-05 EP claimed
US-10781222-B2 Surface treating agent including perfluoro(poly)ether-group-containing silane compound DAIKIN INDUSTRIES, LTD. (JP) 2020-09-22 US claimed
US-10703932-B2 Surface treating agent including perfluoro(poly)ether-group-containing silane compound DAIKIN INDUSTRIES, LTD. (JP) 2020-07-07 US claimed
CN-107709506-B Surface treating agent containing perfluoro (poly) ether group-containing silane compound 大金工业株式会社 2020-06-16 CN claimed
US-20180186820-A1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2018-07-05 US claimed
EP-3315579-A1 SURFACE TREATMENT AGENT INCLUDING PERFLUORO(POLY)ETHER GROUP-CONTAINING SILANE COMPOUND Daikin Industries, Ltd. (JP) 2018-05-02 EP claimed
US-20160340544-A1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2016-11-24 US claimed
EP-3088487-A1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND Daikin Industries, Ltd. (JP) 2016-11-02 EP claimed
EP-0077853-B1 NOVEL TRIFLUOROMETHYL BENZAL CHLORIDES AND PROCESS FOR THE PREPARATION THEREOF OCCIDENTAL CHEMICAL CORPORATION (US) 1985-03-13 EP claimed
EP-0077853-A1 Novel trifluoromethyl benzal chlorides and process for the preparation thereof OCCIDENTAL CHEMICAL CORPORATION (US) 1983-05-04 EP claimed
US-4367348-A Novel trifluoromethyl benzal chlorides and process for the preparation thereof OCCIDENTAL CHEMICAL CORPORATION (US) 1983-01-04 US claimed
CN-120136807-A Thiazolidinedione compounds and application thereof 山东第一医科大学(山东省医学科学院) 2025-06-13 CN disclosed
CN-119350267-B Substituted thiazolidinedione compounds and application thereof 山东第一医科大学(山东省医学科学院) 2025-03-07 CN disclosed
CN-119350267-A Substituted thiazolidinedione compounds and application thereof 山东第一医科大学(山东省医学科学院) 2025-01-24 CN disclosed
US-4503276-A Process for separating nitration isomers of substituted benzene compounds MONSANTO COMPANY (US) 1985-03-05 US disclosed
EP-0129528-A1 Process for the preparation of nitro-substituted benzotrifluoride compounds MONSANTO COMPANY (US) 1984-12-27 EP disclosed
EP-0077853-A1 Novel trifluoromethyl benzal chlorides and process for the preparation thereof OCCIDENTAL CHEMICAL CORPORATION (US) 1983-05-04 EP disclosed
US-4367348-A Novel trifluoromethyl benzal chlorides and process for the preparation thereof OCCIDENTAL CHEMICAL CORPORATION (US) 1983-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180186820-A1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND EPCAM, PFAS, SULT1A1 PNMT 1958/4885IDO1 4560/4885TDO2 3462/4885
US-10781222-B2 Surface treating agent including perfluoro(poly)ether-group-containing silane compound EPCAM, PFAS, SULT1A1 PNMT 1958/4885IDO1 4560/4885TDO2 3462/4885
US-10703932-B2 Surface treating agent including perfluoro(poly)ether-group-containing silane compound FRG1, AFF1, F11 PNMT 2760/4885IDO1 4452/4885TDO2 3474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.