Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.63 |
| ▸ | CA1 | P00915 | 2/20 | 0.63 |
| ▸ | CA2 | P00918 | 2/20 | 0.63 |
| ▸ | CA4 | P22748 | 2/20 | 0.63 |
| ▸ | LTA4H | P09960 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | MC5R | P33032 | 5/20 | 0.61 |
| ▸ | MC4R | P32245 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MC3R | P41968 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MC1R | Q01726 | 2/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.51 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27502280 | 0.86 | MC5R (0.59) | LTA4HEPHX2MC5RMC4RCYP1A2 | |
| Hydrochloric Acid SCHEMBL6417210 | 0.85 | MC5R (0.57) | MC5RMC4RCYP1A2ALDH1A1MC3R | |
| SCHEMBL22495340 | 0.81 | GAA (0.63) | CA12CA1CA2CA4LTA4H | |
| SCHEMBL10399489 | 0.81 | KDM4E (0.84) | CA12CA1CA2CA4LTA4H | |
| SCHEMBL27688886 | 0.81 | KDM4E (0.84) | CA12CA1CA2CA4LTA4H | |
| SCHEMBL28746131 | 0.81 | CYP1A2 (0.58) | MC4RCYP1A2 | |
| SCHEMBL30436899 | 0.79 | CYP1A2 (0.55) | LTA4HEPHX2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6008141 | 0.78 | MC5R (0.71) | CA12CA1CA2CA4MC5R | |
| SCHEMBL5947593 | 0.78 | LTA4H (0.79) | LTA4HEPHX2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8810102 | 0.76 | LTA4H (0.94) | CA12CA1CA2CA4LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090171091-A1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LIMITED (IN) | 2009-07-02 | — | — | US | claimed |
| US-20090171091-A1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LIMITED (IN) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090171091-A1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CETP, APOB, HDLBP | CA12 4280/4885CA1 4644/4885CA2 4559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.